The role of oxymatrine in regulating TGF-β1 in rats with hepatic fibrosis
Acta cir. bras; 33 (3), 2018
Abstract Purpose: To investigate whether oxymatrine (OMT) prevents hepatic fibrosis in rats by regulating liver transforming growth factor β1 (TGF-β1) level. Methods: Hepatic fibrosis was induced in rats by thioacetamide (TAA). Blood was collected at the end of week 12 to determine the leve...
Alcaloides/farmacología, Aspartato Aminotransferasas/sangre, Cirrosis Hepática Experimental/inducido químicamente, Cirrosis Hepática Experimental/metabolismo, Cirrosis Hepática Experimental/prevención & control, Sustancias Protectoras/farmacología, Quinolizinas/farmacología, Ratas Sprague-Dawley, Factor de Crecimiento Transformador beta1/efectos de los fármacos, Factor de Crecimiento Transformador beta1/metabolismo