BACKGROUND: Myasthenia gravis (MG) is an autoimmune disease marked by fluctuating course of muscle weakness. OBJECTIVES: The current study was designed to evaluate plasma levels of cytokines (IL-2, IL-4, IL-6, IL-10, TNF, IFN-γ, and IL17A) in patients with MG and controls and to investigate whether cyto...
ABSTRACT Introduction: patients undergoing pulmonary resection may experience local or remote complications in the postoperative period due to the inflammatory response, which increases the length of hospital stay and costs. This study objective was to establish an expanded interleukins profile, identi...
Abstract Background: Influenza virus infection is often complicated by a bacterial infection, with this coinfection causing severe pneumonia. If not timely treated, the disease can cause death. Objective: To demonstrate, in animal models, that coinfection with influenza virus and bacteria that affect t...
Coinfección/fisiopatología,
Citocinas/sangre,
Modelos Animales de Enfermedad,
Infecciones por Haemophilus/microbiología,
Infecciones por Haemophilus/fisiopatología,
Ratones Endogámicos BALB C,
Infecciones por Orthomyxoviridae/fisiopatología,
Infecciones por Orthomyxoviridae/virología,
Infecciones Neumocócicas/microbiología,
Infecciones Neumocócicas/fisiopatología,
Neumonía/microbiología,
Neumonía/fisiopatología,
Neumonía/virología,
Streptococcus pneumoniae/aislamiento & purificación
Introducción. Los probióticos y prebióticos presentan beneficios potenciales en la inflamacióncrónica de las mucosas, incluida la prevención de la enterocolitis necrosante. No obstante, los mecanismos y resultados de estos efectos inmunomoduladores son confusos. El objetivo fue ...
Estudios Prospectivos,
Citocinas/análisis,
Citocinas/sangre,
Simbióticos/administración & dosificación,
Lactoferrina/administración & dosificación,
Probióticos/uso terapéutico,
Prebióticos,
Oligosacáridos/uso terapéutico,
Recién Nacido de muy Bajo Peso,
Leche Humana,
Enterocolitis Necrotizante/prevención & control,
Turquía
França, E E T;
Gomes, J P V;
De Lira, J M B;
Amaral, T C N;
Vilaça, A F;
Júnior, M D S Paiva;
Júnior, U F Elihimas;
Júnior, M A V Correia;
Júnior, L A Forgiarini;
Costa, M J C;
Andrade, M A;
Ribeiro, L C;
De Castro, C M M B.
Early mobilization is beneficial for critically ill patients because it reduces muscle weakness acquired in intensive care units. The objective of this study was to assess the effect of functional electrical stimulation (FES) and passive cycle ergometry (PCE) on the nitrous stress and inflammatory cytome...
Biomarcadores/sangre,
Enfermedad Crítica/rehabilitación,
Enfermedad Crítica/terapia,
Citocinas/sangre,
Estimulación Eléctrica/métodos,
Inflamación/inmunología,
Inflamación/metabolismo,
Unidades de Cuidados Intensivos,
Terapia Pasiva Continua de Movimiento/métodos,
Estrés Nitrosativo/fisiología,
Estrés Oxidativo/fisiología,
Músculo Cuádriceps/fisiopatología,
Respiración Artificial/métodos
BACKGROUND: Spinal cord injury (SCI) is a severe central nervous system trauma. The present study aimed to evaluate the effect of HIF-1α on inflammation in spinal cord injury (SCI) to uncover the molecular mechanisms of anti-inflammation. RESULTS: HIF-1α was reduced in SCI model rats and HIF-1α activa...
Rheumatoid arthritis (RA) is an autoimmune disease of knee joints involving pain and inflammation. Rhoifolin is a plant flavonoid known to have antioxidant and anti-inflammatory properties. This study was taken to identify the effect of rhoifolin on complete Freund's adjuvant (CFA)-induced arthritis in t...
Artritis Experimental/tratamiento farmacológico,
Artritis Experimental/metabolismo,
Artritis Reumatoide/tratamiento farmacológico,
Artritis Reumatoide/metabolismo,
Biomarcadores/sangre,
Citocinas/sangre,
Disacáridos/administración & dosificación,
Flavonoides/administración & dosificación,
Adyuvante de Freund/administración & dosificación,
Glicósidos/administración & dosificación,
Interleucina-1beta/sangre,
Interleucina-6/sangre,
FN-kappa B/efectos de los fármacos,
FN-kappa B/metabolismo,
Estrés Oxidativo/efectos de los fármacos,
Factor de Necrosis Tumoral alfa/sangre
Abstract Aim: Exercise elicits adaptations in several physiological systems, such as the gastrointestinal tract. We evaluated the effects of an acute strength exercise (acute-SE) on gastric satiety and its correlation with creatinine kinase (CK), lactate, and plasma cytokine levels in humans. Methods:...
SUMMARY AIMS Omentin is an adipokine primarily produced by visceral adipose tissue and its reduced levels have been shown to be associate with worse metabolic outcomes. We aimed to study the effects of preoperative ibuprofen on postoperative omentin levels in rats after surgery. METHODS Forty-eight a...
