LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Differential Effect of ITE on the Aryl Hydrocarbon Receptor Signaling in Breast Cancer Tissue: A Histopathological Study

Li, Zhengdong; Cheng, Xiaolin; Zhuang, Zhigang; Wang, Kai.

Int. j. morphol; 41 (5), 2023

SUMMARY: Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that is highly expressed in various types of cancers including breast cancer. However, the role of AhR with its endogenous ligand 2-(1'H-indole-3'-carbonyl)-thiazole-4-carboxylic acid methyl ester (ITE) on the progression...

Indoles/administración & dosificación, Tiazoles/administración & dosificación, Receptores de Hidrocarburo de Aril/efectos de los fármacos, Neoplasias de la Mama/patología, Indoles/farmacología, Tiazoles/farmacología, Receptores de Estrógenos, Inmunohistoquímica, Proliferación Celular/efectos de los fármacos, Citometría de Flujo, Ensayos de Migración Celular, Western Blotting, Línea Celular Tumoral/efectos de los fármacos, Citocromo P-450 CYP1A1/genética, Citocromo P-450 CYP1B1/genética

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Influence of nicotine dependence, current smoking status and gender on CYP1A1, CYP1B1 and CYP2A6 expression in oral squamous cell carcinoma

Almeida, Adriana Ávila; Bandeira, Celso Muller; Alves, Mônica Ghislaine Oliveira; Pascoal, Maria Beatriz Nogueira; Chagas, José Francisco Salles; Neto, Morun Bernardino; Barros, Patrícia Pimentel de; Nunes, Fábio Daumas; Carta, Celina Faig Lima; Almeida, Janete Dias.

Braz. dent. sci; 25 (2), 2022

Objective: Tobacco smoke is composed of cancer-causing chemicals referred to as carcinogens. These carcinogens are metabolized by the enzymes of the cytochrome P450 (CYP) family. Our objective was to evaluate the correlation of tobacco consumption parameters with CYP1A1, CYP1B1 and CYP2A...

Tabaquismo, Carcinoma de Células Escamosas, Carcinoma, Citocromo P-450 CYP1A1, Citocromo P-450 CYP1B1, Citocromo P-450 CYP2A6

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CYP1A1, CYP1B1, GSTM1 and GSTT1 genetic variants and breast cancer risk in Mexican women

García-Martínez, Angélica; Gamboa-Loira, Brenda; Tejero, M Elizabeth; Sierra-Santoyo, Adolfo; Cebrián, Mariano E; López-Carrillo, Lizbeth.

Salud pública Méx; 59 (5), 2017

Abstract: Objective: To evaluate if variants in the genes CYP1A1 (T3801C and A4889G), CYP1B1 (G119T), GSTM1 (indel) and GSTT1 (indel) are associated with breast cancer (BC) among Mexican women. Materials and methods: 952 incident cases with histologically confirmed BC were matched by age (± 5 years)...

África/etnología, Neoplasias de la Mama/epidemiología, Neoplasias de la Mama/genética, Estudios de Casos y Controles, Citocromo P-450 CYP1A1/genética, Citocromo P-450 CYP1B1/genética, Glutatión Transferasa/genética, Mutación INDEL, México/epidemiología, Reacción en Cadena de la Polimerasa Multiplex, Polimorfismo de Nucleótido Simple, Riesgo

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