HCMV UL97 phosphotransferase gene mutations may be associated with antiviral resistance in immunocompromised patients in Belém, PA, Northern Brazil
Rev. Soc. Bras. Med. Trop; 51 (2), 2018
Abstract INTRODUCTION: Human cytomegalovirus is one of the causes of opportunist infections in immunocompromised patients, and is triggered by factors such as state of viral latency, weakened immune responses, and development of antiviral resistance to ganciclovir, the only drug offered by the public h...
Antivirales/farmacología, Antivirales/uso terapéutico, Estudios de Casos y Controles, Estudios Transversales, Citomegalovirus/efectos de los fármacos, Citomegalovirus/enzimología, Citomegalovirus/genética, Infecciones por Citomegalovirus/tratamiento farmacológico, Farmacorresistencia Viral/efectos de los fármacos, Farmacorresistencia Viral/genética, Genotipo, Huésped Inmunocomprometido, Mutación/genética, Fosfotransferasas/genética, Reacción en Cadena de la Polimerasa