Genotyping single-nucleotide polymorphism CYP2C19*2, pharmacodynamic evaluation of high on-clopidogrel treatment platelet reactivity and the cardiologist
Arch. cardiol. Méx; 90 (4), 2020
Results: 3
Association of CYP2C19*2 polymorphism with clopidogrel resistance among patients with high cardiovascular risk in Northeastern Mexico
Arch. cardiol. Méx; 89 (4), 2019
abstract Objective: Oral antiplatelet drugs are a key to modern pharmacotherapy in cardiovascular atherothrombotic diseases. Clopidogrel (CLO) constitutes the main preventive treatment of atherothrombosis. However, a considerable inter-individual variation in CLO response has been documented, resulting ...
Alelos, Enfermedades Cardiovasculares/tratamiento farmacológico, Enfermedades Cardiovasculares/fisiopatología, Clopidogrel/administración & dosificación, Clopidogrel/farmacología, Citocromo P-450 CYP2C19/genética, Resistencia a Medicamentos/genética, México, Inhibidores de Agregación Plaquetaria/administración & dosificación, Inhibidores de Agregación Plaquetaria/farmacología, Polimorfismo de Nucleótido Simple, Factores de Riesgo
Is preoperative clopidogrel resistance a predictor of bleeding and risks in patients undergoing emergency cabg surgery?
Rev. bras. cir. cardiovasc; 33 (4), 2018
Abstract Objective: The aims of this study were to determine whether the detection of preoperative clopidogrel resistance in patients undergoing cardiac surgery while using clopidogrel could play a guiding role in the prediction of postoperative excessive bleeding, transfusion requirements, and risks an...
Transfusión Sanguínea, Clopidogrel/farmacología, Puente de Arteria Coronaria/efectos adversos, Resistencia a Medicamentos, Inhibidores de Agregación Plaquetaria/farmacología, Pruebas de Función Plaquetaria/métodos, Hemorragia Posoperatoria/diagnóstico, Hemorragia Posoperatoria/etiología, Valor Predictivo de las Pruebas, Periodo Preoperatorio, Estudios Prospectivos, Valores de Referencia, Medición de Riesgo/métodos, Factores de Riesgo, Estadísticas no Paramétricas