Results: 2

Increasing pinosylvin production in Escherichia coli by reducing the expression level of the gene fabI-encoded enoyl-acyl carrier protein reductase

Salas-Navarrete, Caheri; Hernández-Chávez, Georgina; Flores, Noemí; Martínez, Luz María; Martinez, Alfredo; Bolívar, Francisco; Barona-Gomez, Francisco; Gosset, Guillermo.

Electron. j. biotechnol; 33 (), 2018

Background: The plant secondary metabolite pinosylvin is a polyphenol from the stilbene family, which have positive effects on human health. Biotechnological production is an attractive alternative for obtaining this stilbene. In Escherichia coli, malonyl-CoA is the precursor for both stilbene and fatty ...

Estilbenos/metabolismo, Escherichia coli/metabolismo, Enoil-ACP Reductasa (NADH)/genética, Ingeniería Metabólica, Coenzima A Ligasas, Ácidos Grasos, Productos Biológicos

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A diagnostic approach for neurodegeneration with brain iron accumulation: clinical features, genetics and brain imaging

Salomão, Rubens Paulo Araújo; Pedroso, José Luiz; Gama, Maria Thereza Drumond; Dutra, Lívia Almeida; Maciel, Ricardo Horta; Godeiro-Junior, Clécio; Chien, Hsin Fen; Teive, Hélio A G; Cardoso, Francisco; Barsottini, Orlando G P.

Arq. neuropsiquiatr; 74 (7), 2016

ABSTRACT Neurodegeneration with brain iron accumulation (NBIA) represents a heterogeneous and complex group of inherited neurodegenerative diseases, characterized by excessive iron accumulation, particularly in the basal ganglia. Common clinical features of NBIA include movement disorders, particularly p...

Alopecia/diagnóstico por imagen, Alopecia/genética, Arritmias Cardíacas/diagnóstico por imagen, Arritmias Cardíacas/genética, Enfermedades de los Ganglios Basales/diagnóstico por imagen, Enfermedades de los Ganglios Basales/genética, Ceruloplasmina/deficiencia, Ceruloplasmina/genética, Coenzima A Ligasas/genética, Diabetes Mellitus/diagnóstico por imagen, Diabetes Mellitus/genética, Trastornos Heredodegenerativos del Sistema Nervioso/diagnóstico por imagen, Trastornos Heredodegenerativos del Sistema Nervioso/genética, Hipogonadismo/diagnóstico por imagen, Hipogonadismo/genética, Trastornos del Metabolismo del Hierro/diagnóstico por imagen, Trastornos del Metabolismo del Hierro/genética, Distrofias Neuroaxonales/diagnóstico por imagen, Distrofias Neuroaxonales/genética, Mutación, Neuroimagen/métodos

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