Detection of sputum cofilin-1 as indicator of malignancy
Braz. j. med. biol. res; 51 (8), 2018
Cofilin-1 (CFL1), a small protein of 18 kDa, has been studied as a biomarker due to its involvement in tumor cell migration and invasion. Our aim was to evaluate CFL1 as an indicator of malignancy and aggressiveness in sputum samples. CFL1 was analyzed by ELISA immunoassay in the sputum of 73 lung cancer...
Biomarcadores de Tumor/análisis, Carcinoma de Células Escamosas/química, Carcinoma de Células Escamosas/mortalidad, Carcinoma de Células Escamosas/patología, Estudios de Casos y Controles, Proliferación Celular, Cofilina 1/análisis, Ensayo de Inmunoadsorción Enzimática, Neoplasias Pulmonares/química, Neoplasias Pulmonares/mortalidad, Neoplasias Pulmonares/patología, Invasividad Neoplásica, Estadificación de Neoplasias, Pronóstico, Curva ROC, Sensibilidad y Especificidad, Esputo/química