LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Electrocardiographic effect of artemisinin-piperaquine, dihydroartemisinin-piperaquine, and artemether-lumefantrine treatment in falciparum malaria patients

Wu, Wanting; Lu, Chenguang; Liang, Yuan; Zhang, Hongying; Deng, Changsheng; Wang, Qi; Xu, Qin; Tan, Bo; Zhou, Chongjun; Song, Jianping.

Rev. Soc. Bras. Med. Trop; 54 (), 2021

Abstract INTRODUCTION: Artemisinin-based combination therapy (ACT), such as artemisinin-piperaquine (AP), dihydroartemisinin-piperaquine (DP), and artemether-lumefantrine (AL), is the first-line treatment for malaria in many malaria-endemic areas. However, we lack a detailed evaluation of the cardiotox...

Antimaláricos/efectos adversos, Arteméter/uso terapéutico, Combinación Arteméter y Lumefantrina/uso terapéutico, Artemisininas/efectos adversos, Combinación de Medicamentos, Electrocardiografía, Malaria/tratamiento farmacológico, Malaria Falciparum/tratamiento farmacológico, Quinolinas

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Therapeutic failure after regimen with artemether-lumefantrine combination therapy: a report of three cases in Benin City, Nigeria

Abstract Artemisinin-based combination therapy (ACT) is recommended by the World Health Organization for the treatment of uncomplicated malaria. Currently, there appears to be a downward trend in the efficacy of ACT in some parts of sub-Saharan Africa because some patients have been positive for Plasmodi...