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Degradation of mitochondrial structure and deficiency of complex I were associated with the transgenic CMS of rice

Tang, Danfeng; Wei, Fan; Khan, Aziz; Munsif, Fazal; Zhou, Ruiyang.
Biol. Res; 54 (), 2021
BACKGROUND: Mitochondria play a significant role in plant cytoplasmic male sterility (CMS). In our previous study, mitochondrial complex I genes, nad4, nad5, and nad7 showed polymorphisms between the transgenic CMS line M2BS and its wild type M2B. The sterility mechanism of the M2BS at cytological, physi...
Complejo I de Transporte de Electrón/genética, Mitocondrias/patología, Oryza/genética, Infertilidad Vegetal, Regulación de la Expresión Génica de las Plantas, Peróxido de Hidrógeno, Mitocondrias/ultraestructura, Plantas Modificadas Genéticamente
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Evaluating the clinical significance of SHMT2 and its co-expressed gene in human kidney cancer

Wang, Huan; Chong, Tie; Li, Bo-Yong; Chen, Xiao-San; Zhen, Wen-Bo.
Biol. Res; 53 (), 2020
BACKGROUND: Kidney cancer is one of the most common cancers in the world. It is necessary to clarify its underlying mechanism and find its prognostic biomarkers. Current studies showed that SHMT2 may be participated in several kinds of cancer. METHODS: Our studies investigated the expression of SHMT2 in ...
Complejo I de Transporte de Electrón/genética, Glicina Hidroximetiltransferasa/genética, Neoplasias Renales/genética, Neoplasias Renales/patología, Biomarcadores de Tumor/genética, Regulación Neoplásica de la Expresión Génica, Estadificación de Neoplasias, ARN Mensajero
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