Lactate-upregulation of lactate oxidation complex-related genes is blunted in left ventricle of myocardial infarcted rats
Braz. j. med. biol. res; 51 (11), 2018
Lactate modulates the expression of lactate oxidation complex (LOC)-related genes and cardiac blood flow under physiological conditions, but its modulatory role remains to be elucidated regarding pathological cardiac stress. The present study evaluated the effect of lactate on LOC-related genes expressio...
Catalasa/análisis, Expresión Génica, Ventrículos Cardíacos/efectos de los fármacos, Ventrículos Cardíacos/metabolismo, Ácido Láctico/análisis, Ácido Láctico/metabolismo, Ácido Láctico/farmacología, Complejos Multienzimáticos/análisis, Infarto del Miocardio/genética, Infarto del Miocardio/metabolismo, NADH NADPH Oxidorreductasas/análisis, Perfusión, Ratas Wistar, Factores de Tiempo