O processo de compressão representa uma etapa crucial e dinâmica na indústria farmacêutica. É por meio dessa operação que os comprimidos são produzidos, destacando-se como a forma farmacêutica mais prevalente no mercado devido à sua ampla aceitação pelos pacientes, atribuída à facilidade de...
Comprimidos/farmacología,
Industria Farmacéutica/clasificación,
Apoyo a la Formación Profesional/clasificación,
Biofarmacia/clasificación,
d0487880,
Equipos y Suministros/efectos adversos,
ddcs0167350,
ddcs0285700,
d0105920,
d0099340,
d0148940,
d0043640,
Química Farmacéutica/instrumentación
Abstract The objective of the present investigation was to design, optimize and characterize the gastro retentive floating levofloxacin tablets and perform in-vivo evaluation using radiographic imaging. The floating tablets were prepared by using polymers i.e hydroxy propyl methyl cellulose (HPMC-K4M) an...
Abstract Red lima bean (Phaseolus lunatus Linn) Family Fabaceae, has been modified by succinylation and annealing, and used as intra- and extra-granular disintegrants at concentrations of 5 and 10 %w/w in paracetamol tablet formulation in comparison with corn starch BP. The starches were characterised us...
Tizanidine hydrochloride is a centrally acting skeletal muscle relaxant, used in the management of spasticity. This drug is commercially available only as tablets, which highlights the need to develop oral liquid formulations. In the hospital environment, this aspect is circumvented by the preparation of...
Buccal route of administration has many advantages such as improving patient compliance, bypassing the GIT and hepatic first pass effect. The objectives are to formulate mucoadhesive buccal tablet using Mefenamic acid and compatible excipients, and to evaluate the product using quality control tests and ...
Coelho, Angélica Gomes;
Lima Neto, José de Sousa;
Moura, Arkellau Kenned Silva;
Morais, Ilmara Cecilia Pinheiro da Silva;
Cunha, Francisco Valmor Macedo;
Melo-Neto, Bernardo;
Medeiros, Maria das Graças Freire de;
Vasconcelos, Eilika Andreia Feitosa;
Arcanjo, Daniel Dias Rufino;
Nunes, Lívio Cesar Cunha;
Citó, Antônia Maria das Graças Lopes.
ABSTRACT Lippia origanoides is a honey shrub which has showed hypotensive potential assessed by in vivo studies. The aim of this work is the development of a pharmaceutical formulation composed by an optimized extract obtained from aerial parts of L. origanoides. The quantification of the naringenin mark...
O tratamento farmacológico de patologias bucais é conduzido, geralmente, por via de adminis-tração local. No entanto, devido ao pouco tempo de permanência do fármaco no local de ação, esse tratamento pode ser bastante comprometido. Assim, este trabalho teve por objetivo o de-senvolvimento de form...
Sildenafil citrate (SILC) is a potent phosphodiesterase-5 inhibitor used for erectile dysfunction and pulmonary hypertension. This study shows two simple, fast and alternative analytical methods for SILC determination by non-aqueous titration and by derivative ultraviolet spectrophotometry (DUS) in activ...
ABSTRACT Spironolactone (SPR) is a steroidal drug administered as a potassium-sparing diuretic for high blood pressure treatment. The drug shows incomplete gastrointestinal absorption due to its poor aqueous solubility. The physicochemical properties of SPR in crystal forms I and II suggest that differen...
The aim of present study was the assessment of antimicrobial activity of prepared time-dependent release bilayer tablets of amoxicillin trihydrate and in vitro evaluation of drug release by antimicrobial assay using agar plate diffusion method. The bilayer tablets comprised of a delayed and sustained rel...
