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Development of fast dispersing tablets of nebivolol: experimental and computational approaches to study formulation characteristics

Braz. j. pharm. sci; 50 (4), 2014
Formulation of FDT (fast dispersing tablets) of nebivolol was optimized and evaluated using simplex lattice design (SLD). The influence of type and concentration of three disintegrants viz., Ac-Di-Sol, Primojel and Polyplasdone XL on hardness, friability and disintegration time of tablet was studied. Res...