Cota tinctoria is a medicinal plant which has been used for management of cancer in folk medicine of various regions. The aim of present study is to investigate cytotoxic activity of different concentrations of hydroalcoholic extract of C. tinctoria flowers on gastric (AGS) and liver (Hep-G2) cancer ce...
Asteraceae/química,
Extractos Vegetales/administración & dosificación,
Neoplasias Hepáticas/tratamiento farmacológico,
Extractos Vegetales/farmacología,
Línea Celular Tumoral/efectos de los fármacos,
Anthemis/química,
Células Hep G2/efectos de los fármacos,
Neoplasias Gástricas/tratamiento farmacológico,
Antineoplásicos Fitogénicos/administración & dosificación,
Antineoplásicos Fitogénicos/farmacología,
Extractos Vegetales/química,
Antineoplásicos Fitogénicos/química,
Técnicas de Cultivo de Célula,
Compuestos Fenólicos/análisis,
Flavonoides/análisis
Marchi, Juliana Pelissari;
Lívero, Francislaine Aparecida dos Reis;
Soare, Andreia Assuncao;
da Silva, Glacy Jaqueline;
Soares, Ana Karina Vargas;
Giarolo, Camila Moreno;
Jacomassi, Ezilda;
de Souza, Lauro Mera;
Bartolucci, Wanessa de Campos;
Gazim, Zilda Cristiani;
Campos, Caio Franco de Araújo Almeida;
Goncalves, José Eduardo;
Araújo, Cintia de Souza Alferes;
Wietzikoski, Samantha;
Lovato, Evellyn Claudia Wietzikoski.
Epidemiological evidence indicates that plant antioxidants activity can treat or help to prevent the development of various diseases. One species with great potential as an antioxidant is Curcuma longa. However, different extraction techniquescan influence isolated chemical compounds. This study invest...
Curcuma/química,
Antioxidantes/farmacología,
Antioxidantes/química,
Suplementos Dietéticos,
Compuestos Fenólicos/análisis,
Radicales Libres,
Extractos Vegetales/farmacología,
Extractos Vegetales/química,
Fitoterapia,
Cromatografía de Gases y Espectrometría de Masas,
Diarilheptanoides/química
A comparative study was perfomed with conventional and ultrasound assisted extraction on tomato processing waste. Ultrasound extraction exhibited slightly higher phenolic and flavonoids content, as well as higher ABTS + radical scavenging capacity (4.63 mg GAE.g-1, 0.96 mg RUE.g-1 and 27.90 μmol TE.g -1...
Lophophytum species are holoparasites that grow on tree roots. The objectives of the work were to explore the chemical composition of the tubers of two Lophophytum species and to analyze the antioxidant, anti-inflammatory and antilithiatic activity of their extracts using in vitro methods. The chemical ...
Balanophoraceae/química,
Antioxidantes/química,
Antiinflamatorios/química,
Extractos Vegetales/química,
Extractos Vegetales/farmacología,
Antioxidantes/farmacología,
Antiinflamatorios/farmacología,
Cromatografía Líquida de Alta Presión,
Espectrometría de Masas en Tándem,
Compuestos Fenólicos/análisis,
Flavanonas/análisis,
Flavonas/análisis
The objective of the work was to determine the antioxidant potential in vitro of freeze-dried peel extracts of 20 fruits from the northern region of Peru through five tests (Folin-Ciocalteu, DPPH., ABTS+., FRAP and CUPRAC). According to multivariate statistical analyzes, five groups were found: (i.) pe...
We aimed to investigate the effects of Calendula officinalis and Echinacea purpurea extracts in terms of growth parameters, antibacterial activity and phenolic profile in tomato infected by Clavibacter michiganensis subsp. michiganensis (CmmT7). A significant difference was observed in E. purpuraextrac...
Calendula/química,
Echinacea/química,
Antibacterianos/farmacología,
Antibacterianos/química,
Clavibacter/efectos de los fármacos,
Enfermedades de las Plantas,
Solanum lycopersicum,
Plantas Medicinales,
Extractos Vegetales/farmacología,
Extractos Vegetales/química,
Hojas de la Planta,
Compuestos Fenólicos/análisis,
Pruebas de Sensibilidad Microbiana
Microsechium helleri (Cucurbitaceae) has been used in ethnopharmacological as a lotion to prevent hair loss, diuretic and cathartic, in the region of central Veracruz, Mexico is used as antidiabetic. The antioxidant properties of the hexanic (EHex), chloroformic (ECHCl3) and ethanolic (EEtOH) extracts, ...
Cucurbitaceae/química,
Antiinflamatorios/farmacología,
Hipoglucemiantes/farmacología,
Cardiotónicos/farmacología,
Extractos Vegetales/farmacología,
Medicina Tradicional,
México,
Antiinflamatorios/química,
Hipoglucemiantes/química,
Cardiotónicos/química,
Extractos Vegetales/química,
Depuradores de Radicales Libres,
Compuestos Fenólicos/análisis
Figueiredo Júnior, Ernani Canuto;
Cavalcanti, Yuri Wanderley;
Lira, Andressa Brito;
Pessoa, Hilzeth de Luna Freire;
Lopes, Wilton Silva;
da Silva, Diego Romário;
Freires, Irlan Almeida;
Rosalen, Pedro Luiz;
Costa, Edja Maria Melo de Brito;
Pereira, Jozinete Vieira.
This study determined phytochemical composition, antifungal activity and toxicity in vitro and in vivo of Syzygium cumini leaves extract (Sc). Thus, was characterized by gas chromatography coupled to mass spectrometry and submitted to determination of Minimum Inhibitory (MIC) and Fungicidal concentrati...
Syzygium/química,
Extractos Vegetales/química,
Extractos Vegetales/farmacología,
Extractos Vegetales/toxicidad,
Antifúngicos/química,
Antifúngicos/farmacología,
Antifúngicos/toxicidad,
Hojas de la Planta/química,
Pruebas de Sensibilidad Microbiana,
Candida/efectos de los fármacos,
Pruebas de Toxicidad,
Cromatografía de Gases y Espectrometría de Masas,
Antioxidantes,
Compuestos Fenólicos/análisis
Reactive oxygen species are implicated in multiple pathological conditions including erectile dysfunction. This study evaluated the in vitro and in vivo antioxidant potential of the methanolic extracts of Inula glomerata and Salacia kraussii. The plant materials were pulverized and extracted with methan...
Inula/química,
Asteraceae/química,
Salacia/química,
Celastraceae/química,
Antioxidantes/química,
Antioxidantes/farmacología,
Estrés Oxidativo/efectos de los fármacos,
Especies Reactivas de Oxígeno,
Extractos Vegetales/química,
Extractos Vegetales/farmacología,
Compuestos Fenólicos/análisis,
Flavonoides/análisis,
Fitoquímicos/análisis,
Óxido Nítrico/metabolismo,
Ácidos Sulfónicos/metabolismo,
Benzotiazoles/metabolismo,
Ratas Sprague-Dawley
Medeiros, Scheila;
Maia, Thayná Patachini;
Lima, Aline Barbosa;
Pscheidt, Luana Carla;
Delmonego, Larissa;
Vincenzi, Karine Louize;
Custodio, Bruna Vanzin;
Dal Magro, Débora Delwing;
Barauna, Sara Cristiane;
Alberton, Michele Debiasi;
Pereira, Eduardo Manoel;
Delwing-de Lima, Daniela.
We investigated the effects of dichloromethane extract (DME) from Myrcia splendenson alterations caused by type 2 diabetes in the blood and kidney of rats, in order to reduce side effects caused by synthetic drugs. Rats received streptozotocin (60 mg/kg),15 minutes after nicotinamide (120 mg/kg) or water...
Myrtaceae/química,
Diabetes Mellitus Experimental/tratamiento farmacológico,
Extractos Vegetales/administración & dosificación,
Cloruro de Metileno/administración & dosificación,
Hipolipemiantes/administración & dosificación,
Hipoglucemiantes/administración & dosificación,
Antioxidantes/administración & dosificación,
Extractos Vegetales/química,
Compuestos Fenólicos/análisis,
Estrés Oxidativo/efectos de los fármacos,
Cromatografía Líquida de Alta Presión,
Espectrometría de Masa por Ionización de Electrospray,
Ratas Wistar,
Glucemia/efectos de los fármacos,
Estreptozocina
