Results: 13

Lactadherin immunoblockade in small extracellular vesicles inhibits sEV-mediated increase of pro-metastatic capacities

Biol. Res; 57 (), 2024
BACKGROUND: Tumor-derived small extracellular vesicles (sEVs) can promote tumorigenic and metastatic capacities in less aggressive recipient cells mainly through the biomolecules in their cargo. However, despite recent advances, the specific molecules orchestrating these changes are not completely define...

A invenção de um setting on-line para atendimento psicológico remoto

Psicol. ciênc. prof; 43 (), 2023
Com o advento da covid-19, foi declarado estado de emergência de saúde pública e decretadas medidas de isolamento e distanciamento social para conter a propagação da doença. O Conselho Federal de Psicologia, considerando a importância do acolhimento seguro durante a pandemia, publicou a Resoluçã...
Psicología, Servicios de Contestadora, Teletrabajo, Intervención basada en la Internet, Actitud, COVID-19, ddcs0502960, d0033760, d0012880, d0000857620, d0041940, d0046300, d0103560, d0588730, d0012960, d0116340, d0139950, d0138120, Contaminación del Aire, Empleos Subvencionados, Estudiantes, Universidades, Habla, Esfuerzo de Escucha, Muerte, Aflicción, Códigos de Ética, Aplicaciones de la Informática Médica, , Áreas de Influencia de Salud, Entrenamiento Cognitivo, , Imágenes en Psicoterapia, Procesos Psicoterapéuticos, Intervención en la Crisis (Psiquiatría), Intervención Psicosocial, Control de Enfermedades Transmisibles, Control de Infecciones, Exámenes Obligatorios, Cuarentena, Precauciones Universales, Actitud hacia los Computadores, Docentes, Trabajo, Tareas del Hogar, Familia, Padres Solteros, , Enseñanza, Aprendizaje, Horas de Trabajo, Adhesión Celular, Seguridad, Privacidad, Apego a Objetos, Centros de Ocio y Convivencia, Factores Socioeconómicos, Socialización, Distrés Psicológico, Depresión, Ansiedad, Confidencialidad, Comunicación Celular, Comunicación, Respeto, Tristeza, Esperanza de Vida, Esperanza, Calidad de Vida, Bienestar Psicológico, Satisfacción Personal, Conducta, Equilibrio entre Vida Personal y Laboral, Desempleo, Reinserción al Trabajo, Acontecimientos que Cambian la Vida, Psicología Social, Conducta y Mecanismos de Conducta, Estilo de Vida Saludable, Internet, Pertenencia, Identificación Social, Miedo, Diversidad, Equidad e Inclusión, Autonomía Personal, Humanidades, Individualidad, Ubicación de la Práctica Profesional, Capacitación Profesional, Modelo Transteórico, Trastornos del Inicio y del Mantenimiento del Sueño, Cohesión Social, Solidaridad, Relaciones Familiares, Relaciones Interpersonales, Integración Social, Habilidades Sociales, Confianza, Valores Sociales, Salud Mental, Preceptoría, Tutoría, Prevención de Enfermedades, Ajuste Emocional, Escolaridad, Optimismo, Motivación, Psicoanálisis, Inteligencia Emocional

Extracellular signals regulate the biogenesis of extracellular vesicles

Biol. Res; 55 (), 2022
Extracellular vesicles (EVs) are naturally released membrane vesicles that act as carriers of proteins and RNAs for intercellular communication. With various biomolecules and specific ligands, EV has represented a novel form of information transfer, which possesses extremely outstanding efficiency and sp...

MicroRNAs and exosomes: promising new biomarkers in acute myeloid leukemias?

ABSTRACT Despite advances in understanding of carcinogenesis and of treatment of acute myeloid leukemia, this neoplasm still has a lethality of at least 30%. The search for biomarkers that can predict the response to treatment in the early stages of the disease is still necessary. In recent years, a new ...

The luciferase reporter system of the MMP12 endogenous promoter for investigating transcriptional regulation of the human MMP12 gene

Background: Matrix metalloproteinase 12 (MMP12), a member of MMPs, can take lots of roles including extracellular matrix component degradation, viral infection, inflammation, tissue remodeling and tumorigenesis. To explore the transcriptional regulation of MMP12 gene, a sensitive luciferase reporter HEK2...

Perfil proteômico de bactérias presentes em canais radiculares de dentes com periodontite apical sintomática ou assintomática

As infecções endodônticas são causadas por uma comunidade multiespécie de bactérias. Com os métodos de identificação microbiológica e quantificação de endotoxinas, é difícil inferir a fisiologia, a função e a patogenicidade microbiana. Assim, a análise proteômica é uma técnica que pod...

The role of under-investigated connexins in musculoskeletal tissue: a brief review with emphasis on bone tissue

Actual. osteol; 13 (1), 2017
Connexins (Cxs) are a family of transmembrane proteins that form gap junctions and hemi-channels, which mediate cell-cell communication between neighboring cells and the respective extracellular milieu in different tissues. Most tissues and cell types throughout the body express one or more Cx proteins, ...

Management Strategies for Liver Fibrosis

Ann. hepatol; 16 (1), 2017
Abstract: Liver fibrosis resulting from chronic liver injury are major causes of morbidity and mortality worldwide. Among causes of hepatic fibrosis, viral infection is most common (hepatitis B and C). In addition, obesity rates worldwide have accelerated the risk of liver injury due to nonalcoholic fatt...

Effect of CRABP2 on the proliferation and odontoblastic differentiation of hDPSCs

Abstract: Cellular retinoic acid-binding protein 2 (CRABP2) has been detected in several organs during embryonic development. Recent studies have demonstrated that CRABP2 plays important roles in the retinoic acid, β-catenin and Notch signaling pathways, as well as in the interaction between epithel...