Results: 2

Extracellular signals regulate the biogenesis of extracellular vesicles

Jin, Yong; Ma, Lele; Zhang, Wanying; Yang, Wen; Feng, Qiyu; Wang, Hongyang.

Biol. Res; 55 (), 2022

Extracellular vesicles (EVs) are naturally released membrane vesicles that act as carriers of proteins and RNAs for intercellular communication. With various biomolecules and specific ligands, EV has represented a novel form of information transfer, which possesses extremely outstanding efficiency and sp...

Vesículas Extracelulares/metabolismo, Comunicación Celular/fisiología, ARN/metabolismo, Transporte Biológico, Transducción de Señal

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The role of under-investigated connexins in musculoskeletal tissue: a brief review with emphasis on bone tissue

Pacheco-Costa, Rafael; Davis, Hannah M.

Actual. osteol; 13 (1), 2017

Connexins (Cxs) are a family of transmembrane proteins that form gap junctions and hemi-channels, which mediate cell-cell communication between neighboring cells and the respective extracellular milieu in different tissues. Most tissues and cell types throughout the body express one or more Cx proteins, ...

Antiarrítmicos/efectos adversos, Cartílago/metabolismo, Comunicación Celular/fisiología, Conexinas/fisiología, Conexina 43/fisiología, Conservadores de la Densidad Ósea/uso terapéutico, Fenómenos Fisiológicos Celulares, Huesos/metabolismo, Ligamentos/metabolismo, Músculo Esquelético/metabolismo, Osteoblastos/metabolismo, Osteocitos/metabolismo, Resorción Ósea/prevención & control, Tendones/metabolismo, Transducción de Señal/fisiología, Uniones Comunicantes/efectos de los fármacos, Uniones Comunicantes/fisiología