LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Cichoric acid from extracted Echinacea purpurea induces the proliferation and apoptosis of peripheral blood mononuclear cells from yaks

Wang, Meng-jie; Abbas Raza, Sayed Haidar; Wu, Qiang; Xue, Cai-hua; Liu, Jia-hua; Zhang, Long-fei; Zhang, Wen-ying; Wang, Ai-chao; Wu, Hua.

Electron. j. biotechnol; 47 (), 2020

BACKGROUND: Cichoric acid (CA) is extracted from Echinacea purpurea. It is well known and widely used for its immunological function. However, the effect of CA on peripheral blood mononuclear cells (PBMCs) from yaks is still unclear. This study investigated the potential influences of CA on the prolifera...

Echinacea/química, Ácidos Cafeicos/farmacología, Succinatos/farmacología, Proliferación Celular/efectos de los fármacos, Apoptosis/efectos de los fármacos, Factores de Transcripción, Leucocitos Mononucleares/citología, Leucocitos Mononucleares/efectos de los fármacos, Ensayo de Inmunoadsorción Enzimática, Western Blotting, Reacción en Cadena en Tiempo Real de la Polimerasa, RNA-Seq, Citocinas, Concanavalina A/farmacología

Fulltext

Serotonin induces or inhibits neuritic regeneration of leech CNS neurons depending on neuronal identity

Recovery of motor function after central nervous system (CNS) injury is dependent on the regeneration capacity of the nervous system, which is a multifactorial process influenced, among other things, by the role of neuromodulators such as serotonin. The neurotransmitter serotonin can promote neuronal reg...