Results: 3

Eficacia de los factores de crecimiento derivados de plaquetas en el tratamiento de las lesiones condrales y osteocondrales
Effectiveness of platelet-derived growth factors in the treatment of chondral and osteochondral injuries

Rev. Asoc. Méd. Argent; 137 (2), 2024
Las lesiones condrales y osteondrales afectan a sectores del cartílago articular. Producen dolor, inflamación e impotencia funcional que evolucionan a osteoartritis. Los factores de crecimiento presentes en el plasma rico en plaquetas (PRP) son señales bioquímicas capaces de modificar las respuestas ...

PDK2 promotes chondrogenic differentiation of mesenchymal stem cells by upregulation of Sox6 and activation of JNK/MAPK/ERK pathway

Braz. j. med. biol. res; 50 (2), 2017
This study was undertaken to clarify the role and mechanism of pyruvate dehydrogenase kinase isoform 2 (PDK2) in chondrogenic differentiation of mesenchymal stem cells (MSCs). MSCs were isolated from femurs and tibias of Sprague-Dawley rats, weighing 300-400 g (5 females and 5 males). Overexpression and ...

Using mesenchymal stem cells as a therapy for bone regeneration and repairing

Biol. Res; 48 (), 2015
Bone is a unique tissue which could regenerate completely after injury rather than heal itself with a scar. Compared with other tissues the difference is that, during bone repairing and regeneration, after the inflammatory phase the mesenchymal stem cells (MSCs) are recruited to the injury site and diffe...