Results: 4

Effect of amitriptyline on learning and memory consolidation in the male Wistar rats with an experimental model of pentylenetetrazole-induced seizure

Abstract Amitriptyline (AMT) was developed for the treatment of chronic and neuropathic pain. There is also evidence it may be useful in the treatment of neurodegenerative disorders. In this regard, the effect of on the experimental model of seizures and memory impairment caused by seizures in rats is in...

Consolidación y reconsolidación de la memoria. Aproximación teórica al campo educativo
Consolidation and reconsolidation of memory. Theoretical approach to the educational field

El siguiente trabajo tiene como objetivo general la descripción de los procesos neurobiológicos de la consolidación y reconsolidación de la memoria, mientras que el específico, pretende vincular ambos mecanismos con situaciones de enseñanza y de aprendizaje de educación formal. El presente aborda ...

Systemic injection of an H4 receptor agonist induces a decrease in CREB and pCREB levels in the cerebellar vermis and prefrontal cortex in mice

Braz. j. med. biol. res; 52 (5), 2019
Studies have shown that an injection with the histamine H4 receptor agonist VUF-8430 modulates emotional memory processes. In the present study, the aim was to verify if intraperitoneal (ip) injection of VUF-8430 (500 ng/kg) in mice affects the synthesis of proteins required for memory consolidation proc...

Adrenergic receptor β3 is involved in the memory consolidation process in mice

Braz. j. med. biol. res; 51 (10), 2018
Attention and emotion have a positive impact on memory formation, which is related to the activation of the noradrenergic system in the brain. The hippocampus and amygdala are fundamental structures in memory acquisition, which is modulated by noradrenaline through the noradrenergic receptors. Pharmacolo...