LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Differential effect of the route of inoculation of rabies virus on NeuN immunoreactivity in the cerebral cortex of mice

Rengifo, Aura Caterine; Umbarila, Vanessa Jazmin; Garzón, Mary Janeth; Torres-Fernández, Orlando.

Int. j. morphol; 34 (4), 2016

Rabies is a lethal disease caused by a neurotropic virus that produces inconspicuous morphological changes hardly observable with conventional histopathology. The fatal outcome caused by rabies could be attributed to specific biochemical changes that severely impact neuronal function. The neuronal nuclea...

Virus de la Rabia/patogenicidad, Corteza Cerebral/patología, Corteza Cerebral/virología, Inmunohistoquímica, Rabia/metabolismo, Corteza Cerebral/metabolismo, Virus de la Rabia/metabolismo, Proteínas del Tejido Nervioso/análisis, Proteínas Nucleares/análisis

Fulltext

Immunohistochemical overexpression of MAP-2 in the cerebral cortex of rabies-infected mice

The microtubule-associated protein MAP-2 is an integral part of the cytoskeleton and plays an important role in neural morphogenesis. This protein is an essential component of the dendritic cytoskeleton, especially in the adult brain, and its expression can be altered under experimental or pathological c...