11β-hydroxysteroid dehydrogenase type-II activity is affected by grapefruit juice and intense muscular work
Arch. endocrinol. metab. (Online); 61 (6), 2017
ABSTRACT Objective The enzymatic activity of 11β-hydroxysteroid dehydrogenase-2 (11β-HSD2) is key to protecting mineral corticoid receptors from cortisol and has been implicated in blood pressure regulation. Grapefruit juice (GFJ) and acidity are thought to inhibit this enzyme in vitro. This ...
11-beta-Hidroxiesteroide Deshidrogenasa de Tipo 2/antagonistas & inhibidores, 11-beta-Hidroxiesteroide Deshidrogenasa de Tipo 2/sangre, Presión Sanguínea/fisiología, Citrus paradisi, Cortisona/sangre, Estudios Cruzados, Prueba de Esfuerzo, Jugos de Frutas y Vegetales/efectos adversos, Frecuencia Cardíaca/fisiología, Músculo Esquelético/fisiología, Esfuerzo Físico/fisiología