SUMMARY: Carnosine is known as a natural dipeptide, which inhibits the proliferation of tumor cells throughout its action on mitochondrial respiration and cell glycolysis. However, not much is known about its effects on the metabolism of healthy cells. We explored the effects of Karnozin EXTRA® capsule ...
Carnosina/farmacología,
Fibroblastos/efectos de los fármacos,
Riñón/citología,
Supervivencia Celular/efectos de los fármacos,
Metabolismo Energético,
Vimentina/efectos de los fármacos,
Superóxido Dismutasa/efectos de los fármacos,
Técnicas de Cultivo de Célula,
Bioensayo,
Técnica del Anticuerpo Fluorescente,
Cricetinae
SUMMARY: Adipose tissue morphology of different fat tissue depots can be described using the number of adipocytes and cell surface of adipocytes. This study deals with characteristics and morphometric analysis of white and brown adipose tissue depots in healthy adult laboratory mice, hamsters and rats of...
BACKGROUND: Chinese hamster ovary cell line has been used routinely as a bioproduction factory of numerous biopharmaceuticals. So far, various engineering strategies have been recruited to improve the production efficiency of this cell line such as apoptosis engineering. Previously, it is reported that t...
Prolactin (PRL) plays critical roles in regulation of biological functions with the binding of specific prolactin receptor (PRLR). Revealing the expression patterns of PRLR at different developmental stages is beneficial to better understand the role of PRL and its mechanism of action in striped hamsters...
Abstract Oral mucositis is a common inflammatory complication among patients with cancer. This study evaluated the histopathological, stereological, and antioxidant markers of 2% eucalyptus extract in induced oral mucositis in male golden hamsters. In this animal study, oral mucositis was induced in 30 m...
BACKGROUND Visceral leishmaniasis (VL) is a tropical neglected disease with high associated rates of mortality. Several studies have highlighted the importance of the intestinal tract (IT) and gut microbiota (GM) in the host immunological defense. Data in the literature on parasite life cycle and host i...
BACKGROUND: Chinese hamster ovary (CHO) cells are the most commonly used mammalian host cell In the commercial-scale production of biopharmaceutical proteins. Modification of genes involved in apoptosis may improve the productivity of CHO cells. Executive caspases, including caspases 3 and 7, play critic...
BACKGROUND Nanoparticles (NPs) are viable candidates as carriers of exogenous materials into cells via transfection and can be used in the DNA vaccination strategy against leptospirosis. OBJECTIVES We evaluated the efficiency of halloysite clay nanotubes (HNTs) and amine-functionalised multi-walled ca...
Anticuerpos Antibacterianos/inmunología,
Antígenos Bacterianos/administración & dosificación,
Antígenos Bacterianos/inmunología,
Proteínas Bacterianas/administración & dosificación,
Proteínas Bacterianas/inmunología,
Vacunas Bacterianas/administración & dosificación,
Vacunas Bacterianas/inmunología,
Cricetinae,
Modelos Animales de Enfermedad,
Técnica del Anticuerpo Fluorescente Indirecta,
Leptospira interrogans/inmunología,
Leptospirosis/inmunología,
Leptospirosis/prevención & control,
Nanopartículas,
Factores de Transcripción/administración & dosificación,
Factores de Transcripción/inmunología,
Vacunas de ADN/administración & dosificación,
Vacunas de ADN/inmunología
Abstract The role of rodents as reservoirs of helminths of public health importance is not well known. The zoonotic potential of Syphacia spp. has been confirmed; therefore, the study aimed to estimate the occurrence of oxyurid nematodes in small rodents from pet shops and breeding clubs in Slovakia. Fec...
Cricetinae/parasitología,
Heces/parasitología,
Gerbillinae/parasitología,
Cobayas/parasitología,
Ratones/parasitología,
Enfermedades Desatendidas/diagnóstico,
Enfermedades Desatendidas/epidemiología,
Enfermedades Desatendidas/veterinaria,
Oxiuriasis/diagnóstico,
Oxiuriasis/epidemiología,
Oxiuriasis/veterinaria,
Oxyuroidea/clasificación,
Oxyuroidea/aislamiento & purificación,
Mascotas/clasificación,
Mascotas/parasitología,
Prevalencia,
Ratas/parasitología,
Enfermedades de los Roedores/diagnóstico,
Enfermedades de los Roedores/epidemiología,
Enfermedades de los Roedores/parasitología,
Eslovaquia/epidemiología
Abstract INTRODUCTION: Insect cell cultures play an essential role in understanding arboviral replication. However, the replicative efficiency of some of these viruses such as dengue (DENV), yellow fever (YFV), and chikungunya (CHIKV) in a new cellular substrate (Lulo) and in the other two recognized ce...
