LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Development and validation of a HPTLC method for analysis of Sunitinib malate

Hajmalek, Monireh; Goudarzi, Masoumeh; Ghaffari, Solmaz; Attar, Hossein; Mazlaghan, Mehrnoosh Ghanbari.

Braz. j. pharm. sci; 52 (4), 2016

ABSTRACT A simple high performance thin layer chromatography (HPTLC) has been developed and validated for determination of sunitinib malate and possible impurities. The samples were applied in forms of bands on an aluminum TLC plate pre-coated with silica gel and were separated using dichloromethane: met...

Estudio de Validación, Anticarcinógenos/análisis, Cromatografía/clasificación, Cromatografía Líquida de Alta Presión

Fulltext

Chromatographic analysis and antiproliferative potential of aqueous extracts of Punica granatum fruit peels using the Allium cepa test

Punica granatum L., locally known as romanzeira, is native to Asia but found throughout Brazil. P. granatum is used for treating inflammatory, infectious and respiratory diseases. The aim of this study was to evaluate the chromatography and genotoxicity of an aqueous extract of P. granatum (pomegranate) ...