Results: 15

Qualitative Analysis of Baltic Amber Resin by Gas Chromatography Coupled with Mass Spectrometry and the Therapeutic Potential of this Fossil Resin

ABSTRACT Objective: To analyze the molecular composition of a sample of Baltic amber taken from an amber bracelet, verify the presence or absence of compounds beneficial to human health, and discuss the therapeutic potential of this fossil resin. Material and Methods: For this, a qualitative analysis w...

Estudio biodirigido de metabolitos secundarios con actividad antimicrobiana y aislamiento de D-pinitol de semillas de Leucaena esculenta y L. leucocephala

Phytochemical bio-guided studies are used to find compounds with biological activity. Flavonoids from seeds of Leucaena species have antimicrobial activity in strains of medical interest, therefore, fresh seeds were collected from the town of Tlayacapan, Morelos, Mexico. ...

Gestión de riesgos relativo al cambio de campaña productiva durante la etapa de desarrollo tecnológico en una instalación multiproducto
Risk-management related to the productive campaign change during technological development stage in a multi-product facility

Los nuevos paradigmas de la industria farmacéutica en el siglo XXI incorporan el uso de las técnicas de gestión de la calidad, necesarias en el cumplimiento de las buenas prácticas de fabricación en el sector biotecnológico. En este caso de estudio, se aplicó la gestión de riesgo en el cambio de ...

Aplicación del Análisis de Componentes Principales en el proceso de purificación de un biofármaco
Application of Principal Component Analysis in the purification process of a biopharmaceutical

En este trabajo se presenta la aplicación del Análisis de Componentes Principales, mediante el programa THE UNSCRAMBLER versión 8.0, a los datos registrados en un período de 2 años en la etapa de purificación de una planta de producción de Eritropoyetina Humana Recombinante que está basada en var...

Current Approach in Radiochemical Quality Control of the 99mTc-Radiopharmaceuticals: a mini-review

Abstract To present optimized chromatographic systems for radiochemical purity (RCP) evaluation of 99mTc-eluate and 99mTc-radiopharmaceuticals, as well as to assess doses calibrator reliability for routine purposes in hospital radiopharmacies. RCP was determined by different systems and radioactivity was...

Bioprospección de la actividad antimicrobiana de los extractos de los hongos endófitos de Bauhinia guianensis
Bioprospecting of antimicrobial activity of extracts of endophytic fungi from Bauhinia guianensis

Rev. argent. microbiol; 49 (1), 2017
Antibiotic resistance results in higher medical costs, prolonged hospital stays and increased mortality and is rising to dangerously high levels in all parts of the world. Therefore, this study aims to search for new antimicrobial agents through bioprospecting of extracts of endophytic fungi from Bauhini...

Preliminary analysis of Brazilian Amazonian plant extracts using bench-top assays in a through-put basis aiming the identification of potential antioxidant natural product

Plants are a source of compounds that are used for the treatment of human and veterinary diseases. Brazil is one of the richest countries in the world in terms of biodiversity. The present study evaluated extracts using thin-layer chromatography to identify antioxidant activity and determine the presence...

Indole acetic acid and ACC deaminase from endophytic bacteria improves the growth of Solarium lycopersicum

Electron. j. biotechnol; 19 (3), 2016
Background: Endophytic bacteria are ubiquitous in all plant species contributing in host plant's nutrient uptake and helping the host to improve its growth. Moringa peregrina which is a medicinal plant, growing in arid region of Arabia, was assessed for the presence of endophytic bacterial strains. Resul...

Caracterización bioquímica y biológica del veneno de la serpiente Neotropical Macagua (Bothrops Colombiensis) de la región de Barlovento, estado Miranda, Venezuela
Biological and biochemical characterization of the Neotropical Macagua (Bothrops colombiensis) snake venom from Barlovento region, Miranda state, Venezuela

Rev. cuba. med. trop; 67 (2), 2015
Introducción: el veneno de B. colombiensis no es solamente un elemento tóxico; en su composición existen múltiples componentes, que tienen un gran potencial terapéutico, principalmente en el tratamiento de patologías de la trombosis y la coagulación. Objetivos: estudiar una mezcla de venenos de Bo...