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Reverse phase high-performance liquid chromatography for quantification of hydroxymethylnitrofurazone in polymeric nanoparticles

Monteiro, Lis Marie; Tavares, Guilherme Diniz; Ferreira, Elizabeth Igne; Consiglieri, Vladi Olga; Bou-Chacra, Nadia Araci; Löbenberg, Raimar.
Braz. j. pharm. sci; 51 (3), 2015
Hydroxymethylnitrofurazone (NFOH) is a new compound with potential leishmanicidal and trypanocidal activity. Despite its effectiveness, the formulators have to overcome its poor aqueous solubility. Recently, polymeric nano-scale drug delivery systems have proposed for the treatment of neglected diseases....
Cromatografía Liquida/clasificación, Nanopartículas/22074, Cromatografía de Fase Inversa, Enbucrilato, Nitrofurazona/farmacocinética
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Validation of high-performance liquid chromatographic method for analysis of fluconazole in microemulsions and liquid crystals

Silva, Hilris Rocha e; Santos, Fernanda Kolenyak dos; Luz, Gabriela Marielli da; Chorilli, Marlus; Gremião, Maria Palmira Daflon.
Braz. j. pharm. sci; 50 (2), 2014
In recent decades, there has been a significant increase in the incidence of fungal diseases. Certain fungal diseases cause cutaneous lesions and in the usual treatment, generally administred orally, the drug reaches the site of action with difficulty and its concentration is too low. An approach much ex...
Estudios de Validación como Asunto, Cromatografía Liquida/clasificación, Fluconazol/análisis, Cristales Líquidos/clasificación, Nanotecnología/clasificación
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