Results: 2

Compound Danshen Dripping Pills pretreatment protects the heart from ischemia/reperfusion injury by enhancing autophagic flux

Liu, Haiqiong; Liang, Qian; Mei, Xiheng; Li, Hekai; Yan, Jing; Long, Man; Yang, Xili; Wang, Wei; Li, Weijie; Chen, Aihua; Ling, Yuanna.

Braz. J. Pharm. Sci. (Online); 59 (), 2023

Abstract Compound Danshen Dripping Pills (CDDPs) have been used in clinical treatment to protect the heart from ischemia/reperfusion (IR) injury for many years. However, the underlying mechanism implicated in the protective effects remains to be explored. Here, we determined the effects of CDDPs in Sprag...

Ecocardiografía/métodos, d0013430, d0172090, Isquemia/clasificación, Reperfusión/clasificación, Corazón/fisiopatología, Infarto/patología, Microscopía Electrónica de Transmisión/métodos, d0275610, Daño por Reperfusión/clasificación, Western Blotting/instrumentación

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Effects of a new thiazolidine compound (GQ-11) on tissue repair process in models of insulin resistance and ischemia-reperfusion

Silva, Jacqueline Cavalcante.

The thiazolidinediones (TZDs) class comprises drugs with hypoglycemic effects, reducing insulin resistance in peripheral tissues. Our group has demonstrated in preliminary in vivo studies that a new TZD, GQ-11, improves insulin resistance as well as modulates cytokines involved in inflammatory process, s...

Hipoglucemiantes/agonistas, Insulinas, Inflamación/clasificación, Isquemia, Daño por Reperfusión/clasificación

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