ABSTRACT Objective: Evaluate the neurological recovery with a follow-up of 06 (six) months in victims of thoracic and lumbar fractures who underwent spinal decompression in less than 24 hours, between 24 and 48 hours, and more than 48 hours after the trauma. Methods: Data were collected on patients see...
ABSTRACT. Corticobasal degeneration (CBD) is a sporadic tauopathy that presents with a varied combination of motor, cognitive, and behavioral features, making its diagnosis difficult. CBD has high morbidity and poor prognosis, with no effective therapy at present. We searched the PubMed/MEDLINE database ...
Abstract Introduction Riluzole (2-amino-6-trifluoromethoxy benzothiazole) is known as a neuroprotective, antioxidant, antiapoptotic agent. It may have beneficial effects on neuronal cell death due to cisplatin-induced ototoxicity. Objective To evaluate the effect of riluzole on cisplatin-induced otot...
Riluzol/farmacología,
Cisplatino/efectos adversos,
Cobayas,
Umbral Auditivo/efectos de los fármacos,
Microscopía Electrónica de Transmisión,
Potenciales Evocados Auditivos del Tronco Encefálico/efectos de los fármacos,
Células Ciliadas Auditivas/efectos de los fármacos,
Pérdida Auditiva Sensorineural/inducido químicamente,
Estría Vascular/efectos de los fármacos,
Células Ciliadas Auditivas/patología,
Estría Vascular/patología,
Degeneración Nerviosa/inducido químicamente,
Nervio Coclear/efectos de los fármacos,
Nervio Coclear/patología,
Riluzol/uso terapéutico,
Modelos Animales
The Cognitive Reserve (CR) construct seeks to explain the brain's ability of compensate for degeneration caused by age or neuropathology. However, standardized measures of CR are incipient. Through a systematic review, this study aimed to investigate the instruments in the form of scales and questionnair...
Abstract Purpose: To evaluate whether there is a relationship between renal artery vasospasm related low glomerular density or degeneration and neurogenic lung edema (NLE) following subarachnoid hemorrhage. Methods: This study was conducted on 26 rabbits. A control group was formed of five animals, a ...
Beta-glucans (βg), that have many useful effects on human health, are natural polysaccharides. Our aim in this study was to determine useful effect of βg against oxidative and neuronal damage caused by global cerebral ischemia/reperfusion (IR) in stroke imitated mice via surgical operation. A total of ...
ABSTRACT OBJECTIVE: To describe genetic aspects and characteristics associated with premature aging in adults with Down syndrome. METHOD: A cross-sectional study was carried out of 28 individuals with Down syndrome, aged between 20 and 54 years old (13 women and 15 men), in a university community geneti...
Among the neurodegenerative disorders, Parkinson disease (PD) is ranked as second most common. The pathological hallmark is selective degeneration of the dopaminergic neurons in the nigro-striatal regions of brain with appearance of the Lewy bodies. Present study explores the neuro-protective potential o...
Enfermedad de Parkinson/tratamiento farmacológico,
Modelos Animales de Enfermedad,
Ratas Sprague-Dawley,
Glucósidos/administración & dosificación,
Estilbenos/administración & dosificación,
Trastornos del Movimiento/prevención & control,
Fármacos Neuroprotectores,
Rotenona/toxicidad,
Inmunohistoquímica,
Enfermedad de Parkinson/patología,
Degeneración Nerviosa/prevención & control,
Dopamina
A Doença de Parkinson (DP) é um distúrbio neurodegenerativo, caracterizada em parte pela perda de neurônios dopaminérgicos da via nigroestriatal, originada na substância negra com projeções para o estriado, causando vários déficits motores. Atualmente, o tratamento mais utilizado é a administr...
Abstract Introduction: The use of mobile phones has become widespread in recent years. Although beneficial from the communication viewpoint, the electromagnetic fields generated by mobile phones may cause unwanted biological changes in the human body. Objective: In this study, we aimed to evaluate the ...
Apoptosis/efectos de la radiación,
Teléfono Celular,
Núcleo Coclear/patología,
Núcleo Coclear/efectos de la radiación,
Campos Electromagnéticos/efectos adversos,
Potenciales Evocados Auditivos del Tronco Encefálico/efectos de la radiación,
Audición/efectos de la radiación,
Inmunohistoquímica,
Degeneración Nerviosa/etiología,
Exposición a la Radiación/efectos adversos,
Ondas de Radio/efectos adversos,
Ratas Wistar,
Valores de Referencia,
Factores de Riesgo,
Factores de Tiempo
