Long-term treatment with 3, 4-methylenedioxymethamphetamine caused retina damage in C57BL/6 mice
Arq. bras. oftalmol; 82 (5), 2019
ABSTRACT Purpose: As a class of psychostimulant drugs, amphetamines are widely abused for their stimulant, euphoric, and hallucinogenic properties. Many of these effects result from acute increases in dopamine and serotonin neurotransmission. Following the onset of these effects, 3,4 methylenedioxymetha...
Apoptosis/efectos de los fármacos, Western Blotting, Electrorretinografía, Lesiones Oculares/tratamiento farmacológico, Lesiones Oculares/genética, Ratones Endogámicos C57BL, N-Metil-3,4-metilenodioxianfetamina/toxicidad, Estrés Oxidativo/efectos de los fármacos, Degeneración Retiniana/tratamiento farmacológico, Degeneración Retiniana/genética