LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Pharmacological inhibition of mTORC1 activity protects against inflammation-induced apoptosis of nucleus pulposus cells

Lumbar disc herniation is a common disease characterized by the degeneration of intervertebral discs (IVDs), accompanied by imbalance of metabolic and inflammatory homeostasis. Current studies establish that IVD degeneration is induced by increased apoptosis of nucleus pulposus (NP) cells. However, the u...

Clinical management of dogs with presumptive diagnosis of thoracolumbar intervertebral disc disease: 164 cases (2006-2017)

Baumhardt, Raquel; Ripplinger, Angel; Aiello, Graciane; Schwab, Marcelo L; Ferrarin, Denis A; Wrzesinski, Mathias R; Rauber, Julia; Mazzanti, Alexandre.

Pesqui. vet. bras; 40 (1), 2020

This study aimed to identify dogs with presumptive diagnosis of cervical intervertebral disc disease (IVDD) submitted to clinical management and to evaluate the outcomes. Data were obtained from the medical records of patients with neurological dysfunction assisted at a University Veterinary Hospital fro...

Enfermedades de la Columna Vertebral/tratamiento farmacológico, Enfermedades de la Columna Vertebral/veterinaria, Disco Intervertebral/patología, Enfermedades de la Columna Vertebral/terapia, Degeneración del Disco Intervertebral/veterinaria, Degeneración del Disco Intervertebral/tratamiento farmacológico, Degeneración del Disco Intervertebral/terapia, Compresión de la Médula Espinal/veterinaria, Compresión de la Médula Espinal/tratamiento farmacológico, Compresión de la Médula Espinal/terapia

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