Results: 5

Dendritic surface functionalization of nanomaterials: controlling properties and functions for biomedical applications

Braz. j. pharm. sci; 49 (spe), 2013
A wide variety of nanomaterials have demonstrated promise in medical applications such as drug delivery and imaging. In these applications, the surface chemistry of the materials is critical as it plays an important role in determining the toxicity and biodistribution behavior of the material. We review ...

Synthesis and MALDI-ToF characterization of dendronized poly(ethylene glycol)s

Braz. j. pharm. sci; 49 (spe), 2013
Well-defined hybrids of linear poly(ethylene glycol)s (PEGs) and dendritic polyesters were prepared via the dendronization of the alcohol end groups of the mono and difunctional linear PEGs. Though useful for rudimentary product characterization, GPC and NMR could not verify the overall structural purity...

From dendrimers to fractal polymers and beyond

Braz. j. pharm. sci; 49 (spe), 2013
The advent of dendritic chemistry has facilitated materials research by allowing precise control of functional component placement in macromolecular architecture. The iterative synthetic protocols used for dendrimer construction were developed based on the desire to craft highly branched, high molecular ...

Glycodendrimers: versatile tools for nanotechnology

Braz. j. pharm. sci; 49 (spe), 2013
Combining nanotechnology with glycobiology has triggered an exponential growth of research activities in the design of novel functional bionanomaterials (glyconanotechnology). More specifically, recent synthetic advances towards the tailored and versatile design of glycosylated nanoparticles namely glyco...