Abstract Phenolic compounds are widely distributed in the plant kingdom and in the microorganisms. Cinnamic acid and its hydroxylated derivative-ferulic acid, are phenolic compounds. Ferulic acid possesses antioxidant potential, as well as anti-cancer, anti-inflammatory, and antimicrobial properties. It ...
The objective of the work was to determine the antioxidant potential in vitro of freeze-dried peel extracts of 20 fruits from the northern region of Peru through five tests (Folin-Ciocalteu, DPPH., ABTS+., FRAP and CUPRAC). According to multivariate statistical analyzes, five groups were found: (i.) pe...
Search for safe antioxidants and novel nutraceuticals urged to evaluate the antioxidant, anti-acetylcholine esterase and anti-lipoxygenase activity of various leaf extracts of Conocarpus lancifolius. Extraction was optimized from freeze dried plant extracts quenched with liquid nitrogen using water, et...
Combretaceae/química,
Extractos Vegetales/farmacología,
Extractos Vegetales/química,
Antioxidantes/farmacología,
Antioxidantes/química,
Fenoles/análisis,
Flavonoides/análisis,
Inhibidores de la Lipooxigenasa/farmacología,
Inhibidores de la Colinesterasa/farmacología,
Inhibidores de la Lipooxigenasa/química,
Inhibidores de la Colinesterasa/química,
Técnicas In Vitro,
Etanol,
Depuradores de Radicales Libres
Microsechium helleri (Cucurbitaceae) has been used in ethnopharmacological as a lotion to prevent hair loss, diuretic and cathartic, in the region of central Veracruz, Mexico is used as antidiabetic. The antioxidant properties of the hexanic (EHex), chloroformic (ECHCl3) and ethanolic (EEtOH) extracts, ...
Cucurbitaceae/química,
Antiinflamatorios/farmacología,
Hipoglucemiantes/farmacología,
Cardiotónicos/farmacología,
Extractos Vegetales/farmacología,
Medicina Tradicional,
México,
Antiinflamatorios/química,
Hipoglucemiantes/química,
Cardiotónicos/química,
Extractos Vegetales/química,
Depuradores de Radicales Libres,
Compuestos Fenólicos/análisis
BACKGROUND: In fish farming, the plant extracts containing antioxidant compounds have been added to the diet for enhancing pathogen resistance. In vitro studies evaluating the antioxidant effect of herbal extracts on fish cell models have focused on ROS production and the respiratory burst mechanism. How...
Salmón,
Salmo salar,
Extractos Vegetales/farmacología,
Sambucus nigra/química,
Estrés Oxidativo,
Leucocitos,
Polifenoles/farmacología,
Antioxidantes,
Acuicultura,
Depuradores de Radicales Libres,
Peroxidación de Lípido,
Resistencia a la Enfermedad,
Especies Reactivas de Oxígeno
Gatto, Larissa Junqueira;
Oliveira, Gustavo Rezende Bellei de;
Rech, Katlin Suellen;
Moura, Paula Francislaine;
Gribner, Caroline;
Merino, Francis José Zortéa;
Ávila, Suelen;
Dias, Josiane de Fatima Gaspari;
Miguel, Obdulio Gomes;
Miguel, Marilis Dallarmi.
Several species of the Myrcia genus have been used in folk medicine to treat diabetes. Therefore, the aim of this work was to investigate the inhibitory activity of α-glucosidase and pancreatic lipase in the crude extract (EBF) and in the ethyl acetate fraction (FFA) of Myrcia hatschbachii, as well as t...
Myrtaceae/química,
Antioxidantes/farmacología,
Inhibidores de Glicósido Hidrolasas/farmacología,
Lipasa/efectos de los fármacos,
Páncreas/enzimología,
Extractos Vegetales/farmacología,
Extractos Vegetales/toxicidad,
Ácido Gálico,
Ácido Elágico,
Extractos Vegetales/química,
Antioxidantes/química,
Fenoles/análisis,
Difracción de Rayos X,
Depuradores de Radicales Libres,
Técnicas In Vitro,
Mezclas Complejas
Abstract Introduction Cisplatin damages the auditory system and is related to the generation of free radicals. Glutathione peroxidase is an endogenous free radicals remover. Objective To investigate the mechanisms involved in otoprotection by N-acetylcys- teine through the expression of glutathione p...
Estrés Oxidativo/efectos de los fármacos,
Cisplatino/toxicidad,
Glutatión Peroxidasa/metabolismo,
Acetilcisteína/uso terapéutico,
Cisplatino/uso terapéutico,
Ratas Wistar,
Acetilcisteína/metabolismo,
Pérdida Auditiva Sensorineural/prevención & control,
Cóclea/efectos de los fármacos,
Antineoplásicos/toxicidad,
Depuradores de Radicales Libres/uso terapéutico,
Depuradores de Radicales Libres/metabolismo,
Microscopía Electrónica de Rastreo,
Técnica del Anticuerpo Fluorescente,
Potenciales Evocados Auditivos del Tronco Encefálico,
Cóclea/anatomía & histología,
Acetilcisteína/farmacología,
Depuradores de Radicales Libres/farmacología,
Radicales Libres
Zhao, Xiaoying;
Zhang, Erfei;
Ren, Xiaofen;
Bai, Xiaoli;
Wang, Dongming;
Bai, Ling;
Luo, Danlei;
Guo, Zheng;
Wang, Qiang;
Yang, Jianxin.
BACKGROUND: Kidney ischemia-reperfusion injury is a common pathophysiological phenomenon in the clinic. A large number of studies have found that the tyrosine protein kinase/signal transducer and activator of transcription (JAK/STAT) pathway is involved in the development of a variety of kidney diseases ...
This study presents analyses on the chemistry, biology, pharmacology and chromatography of essential oils extracted from three species of the Ocotea genus: O. minor, O. ceanothifolia and O. leucoxylon. Leaves and stems, as well as the bark of O. minor, were processed using a modified Clevenger apparat...
Ocotea/química,
Lauraceae/química,
Aceites Volátiles/química,
Aceites Volátiles/farmacología,
Monofenol Monooxigenasa/antagonistas & inhibidores,
Industria Cosmética,
Cromatografía de Gases y Espectrometría de Masas,
Ionización de Llama,
Sesquiterpenos/análisis,
Depuradores de Radicales Libres,
Óxidos/análisis
Abstract Purpose To evaluate the effect of remote ischemic conditioning associated to N-acetylcysteine (NAC) on testicular ischemia∕reperfusion (I∕R) injury in rats. Methods Twenty-five adult male Wistar rats were randomly distributed into five experimental groups (n=5), as follows: Sham,...
Acetilcisteína/farmacología,
Evaluación Preclínica de Medicamentos,
Depuradores de Radicales Libres/farmacología,
Precondicionamiento Isquémico/métodos,
Estrés Oxidativo/efectos de los fármacos,
Capacidad de Absorbancia de Radicales de Oxígeno,
Distribución Aleatoria,
Ratas Wistar,
Daño por Reperfusión,
Testículo/irrigación sanguínea,
Testículo/efectos de los fármacos
