Razaque, R;
Raza, A. R;
Irshad, M;
Rubab, S. L;
Batool, S;
Nisar, B;
Akram, Z;
Akhtar, M. T;
Qadir, R;
Siddique, Abu Bakar;
Siddique, Farzana;
Saadia, M.
Due to the severe side effects revealed by most of the currently used antidiabetic medicines, search for finding new and safe drugs to manage diabetes is continued. Naphthoquinones possessing strong antioxidant properties have been employed as candidates for diabetes therapy. Present study is aimed at fi...
Abstract Experimental research with the use of animal models to represent a specific reality is a target of criticism by the population. This study analyzed the knowledge of elementary and high school students on experimental/animal research methods, official ethical guidelines/laws, and regulatory insti...
As leishmanioses são doenças vetoriais causadas por protozoários do gênero Leishmania que afetam o sistema fagocítico mononuclear de vertebrados. Consideradas entre as dez principais doenças tropicais negligenciadas pela Organização Mundial da Saúde, têm um impacto significativo em áreas econo...
Resumo O artigo analisa a resposta federal dos Sistemas Nacionais de Vigilância em Saúde e de Vigilância Sanitária frente à epidemia do Zika vírus no Brasil, de 2015 a 2018, com foco nos contextos político-institucionais e no conteúdo das medidas governamentais desenvolvidas no período. O estud...
Virus Zika,
Epidemias,
Aedes,
Vigilancia Sanitaria,
Sistema Nacional de Vigilancia Sanitaria,
Agencia Nacional de Vigilancia Sanitaria,
Infecciones por Arbovirus/prevención & control,
Estrategias de Salud,
Control de Vectores de las Enfermedades,
Programas Nacionales de Salud,
Política Pública,
Urgencias Médicas,
Desarrollo de Medicamentos,
Sistema Único de Salud,
Brasil
Abstract Biological activity of boron-containing compounds (BCCs) has been well-known. Growing interest and numerous applications for BCCs have been reported. Boron and boron-containing acids show low acute toxicity in mammals but data on halogenated boroxine (HB) - dipotassium-trioxohydroxytetrafluorotr...
Desarrollo de Medicamentos/instrumentación,
Boro/agonistas,
Pruebas de Toxicidad Aguda/instrumentación,
Antioxidantes/farmacología,
d0099340,
Productos Biológicos/efectos adversos,
Técnicas In Vitro/métodos,
d0001430,
d0079280,
d0207140,
ddcs0516950
Abstract Bauhinia forficata Link aqueous extract is usually recommended as a phytomedicine to reduce blood glucose levels and its biological activity has been linked to the presence of phenolic compounds from B. forficata preparations. Several drying processes are used in the production of dry herbal ext...
For registration of generic and similar drugs, it is necessary to carry out pharmaceutical equivalence (PE) tests and pharmaceutical bioequivalence (PB). To carry out these tests, duly qualified research centers are contracted, which need to be monitored by the sponsor who is legally responsible for the ...
Doenças negligenciadas impõem um fardo humano, social e econômico devastador a mais de um bilhão de pessoas em todo o mundo. Embora existam ferramentas para controlar e até mesmo eliminar muitas dessas doenças, novos produtos terapêuticos precisam urgentemente ser desenvolvidos. Este artigo se bas...
Introduction: Traditional Chinese Medicine (TCM) represents one of the first holistic approaches in the world to treat and prevent disease. Herbal medicine is one of the major therapeutic remedy in TCM. It often involves multi-herb therapies instead of single herb preparations. Parallel to western medici...
For a drug to excerpt pharmacological action after oral intake, it first needs to be released from the formulation, get into solution (dissolve), be absorbed, and reach the systemic circulation. Since only solubilized drugs can be absorbed, and thus have therapeutic effect, the understanding of the disso...
Optimización de Procesos,
Acciones Farmacológicas,
Composición de Medicamentos,
Concentración de Iones de Hidrógeno,
Desarrollo de Medicamentos/instrumentación,
Eficiencia,
Liberación de Fármacos,
Metronidazol/efectos adversos,
Necesidades y Demandas de Servicios de Salud/clasificación,
Preparaciones Farmacéuticas/análisis,
Química Farmacéutica/instrumentación,
Disolución
