DHEA and frontal fibrosing alopecia: molecular and physiopathological mechanisms
An. bras. dermatol; 91 (6), 2016
Abstract The transforming growth factor-beta 1 (TGFβ1) promotes fibrosis, differentiating epithelial cells and quiescent fibroblasts into myofibroblasts and increasing expression of extracellular matrix. Recent investigations have shown that PPAR (peroxisome proliferator-activated receptor*) is a ne...