Results: 2

Localization of Diacylglycerol Kinase ζ in the Kidney of Adult Rats: Its Dominant Expression in Collecting Tubules and its Selective Lack in Proximal Tubules

Int. j. morphol; 41 (3), 2023
SUMMARY: Diacylglycerol kinase (DGK) exerts balancing the intracellular level between two-second messengers, diacylglycerol and phosphatidic acid, by its phosphorylation activity. DGK ζ is often localized in cell nuclei, suggesting its involvement in the regulation of intranuclear activities, includ...

O papel da proteína quinase C no desenvolvimento das complicações vasculares do diabetes mellitus
Role of protein kinase C in the development of vascular complications of diabetes mellitus

A mortalidade dos pacientes com diabetes (DM) é maior do que a da populaçäo em geral e decorre especialmente das doenças cardiovasculares. Os prováveis mecanismos da aterosclerose acelerada nestes pacientes säo os efeitos tóxicos diretos da glicose sobre a vasculatura, a resistência à insulina e...