Results: 2

Hematological and renoprotective effects of folic acid and lentil extract in diclofenac sodium exposed rats

Abdel-Rahman, Omnia N; Abdel-Baky, Enas S.

Braz. j. biol; 83 (), 2023

Abstract Excessive intake of non-steroidal anti-inflammatory drugs such as, diclofenac sodium (DS) may lead to toxicity in the rats. In this work, we aimed to examine the protective impact of lentil extract (LE) and folic acid (FA) on the hematological markers, the kidney tissue oxidative stress and the ...

Antioxidantes, Diclofenaco/toxicidad, Ácido Fólico, Lens (Planta), Estrés Oxidativo, Extractos Vegetales/farmacología

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A study on the toxic effect of different doses of diclofenac sodium on the development of the kidney in the postnatal period

Mustafa, Hesham N; Alkan, Isinsu; Deniz, Ömür Gülsüm; Altunkaynak, Berrin Zuhal; Annaç, Ebru; Kaplan, Suleyman.

Int. j. morphol; 37 (3), 2019

The toxic effects of different doses of diclofenac sodium (DS) on the kidney on the postnatal period (0-7 days) by morphometrical and immunohistochemical methods were investigated. For this purpose, 15 female adult wistar albino rats were used and divided into 5 main groups. Group Ia served as normal con...

Diclofenaco/toxicidad, Diclofenaco/administración & dosificación, Riñón/efectos de los fármacos, Riñón/crecimiento & desarrollo, Apoptosis/efectos de los fármacos, Animales Recién Nacidos, Túbulos Renales Proximales/efectos de los fármacos, Inmunohistoquímica, Ratas Wistar, Coloración y Etiquetado