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Therapeutic Effects of Dimethyl Fumarate on the Rat Model of Brain Ischemia

Owjfard, Maryam; Bigdeli, Mohammad Reza; Safari, Anahid; Namavar, Mohammad Reza.
Braz. J. Pharm. Sci. (Online); 58 (), 2022
Abstract Blood-brain barrier (BBB) disruption, inflammation, and cell death are major pathogenic mechanisms in ischemic stroke. Dimethyl fumarate (DMF) has anti-inflammatory and immune-modulatory effects. So, this study aimed to elucidate the effects of DMF on brain ischemia in the middle cerebral arter...
Usos Terapéuticos, Dimetilfumarato/efectos adversos, Isquemia Encefálica/patología, Edema Encefálico/patología
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NFORME DE ESTUDIO DE BIOEQUIVALENCIA FUMARATO DE DIMETILO 240 MG MODIFICADO. Cápsulas de liberación en condiciones alimentadas
BIOEQUIVALENCE STUDY REPORT DIMETHYL FUMARATE 240 MG MODIFIED RELEASE CAPSULES UNDER FED CONDITIONS

Anon.
Prensa méd. argent; 103 (10), 2017
All plasma concentrations of subject no. 35 in period II were below the quantification (BLQ ). As there were no significant clinical observations, data 35 were considered for pharmacokinetic and statistical analysis. Hence, data were considered for pharmacokinetic and statistical analysis. However, analy...
Equivalencia Terapéutica, Dimetilfumarato/administración & dosificación, Dimetilfumarato/efectos adversos, Cápsulas/farmacocinética, Estudios de Seguimiento, 50292, Ensayos Clínicos Controlados Aleatorios como Asunto
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