Therapeutic effects of benzoylaconitine and paeoniflorin in rats with collagen-induced arthritis
Braz. J. Pharm. Sci. (Online); 58 (), 2022
Abstract To explore the effects and mechanisms of benzoylaconitine and paeoniflorin on collagen-induced arthritis (CIA) rats. Weight, paw swelling, arthritis index and joint pathologic changes were examined in each group after CIA induction. PGE2, IL-1β, IL-6, IL-10, TNF-α, VEGF, MMP-3, IgG and anti-CI...
Artritis Experimental/inducido químicamente, Usos Terapéuticos, Microscopía Electrónica de Transmisión/métodos, Dinoprostona/efectos adversos, Ensayo de Inmunoadsorción Enzimática/métodos, Interleucina-1/farmacología, Interleucina-10/farmacología, Interleucina-6/farmacología, Metaloproteinasas de la Matriz