Genomic analysis of bifunctional Class C-Class D β-lactamases in environmental bacteria
Mem. Inst. Oswaldo Cruz; 113 (8), 2018
β-lactamases, which are found in several bacterial species and environments, are the main cause of resistance to β-lactams in Gram-negative bacteria. In 2009, a protein (LRA-13) with two β-lactamase domains (one class C domain and one class D domain) was experimentally characterised, and a...