Results: 2

DNA hypermethylation of Fgf16 and Tbx22 associated with cleft palate during palatal fusion

Shu, Xuan; Dong, Zejun; Cheng, Liuhanghang; Shu, Shenyou.

J. appl. oral sci; 27 (), 2019

Abstract Objective: Cleft palate (CP) is a congenital birth defect caused by the failure of palatal fusion. Little is known about the potential role of DNA methylation in the pathogenesis of CP. This study aimed to explore the potential role of DNA methylation in the mechanism of CP. Methodology: We es...

Fisura del Paladar/embriología, Fisura del Paladar/genética, Fisura del Paladar/patología, Metilación de ADN, Factores de Crecimiento de Fibroblastos/análisis, Factores de Crecimiento de Fibroblastos/genética, Expresión Génica, Ratones Endogámicos C57BL, Dominios y Motivos de Interacción de Proteínas, Reacción en Cadena en Tiempo Real de la Polimerasa, Valores de Referencia, Análisis de Secuencia de ADN, Proteínas de Dominio T Box/análisis, Proteínas de Dominio T Box/genética

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Liver proteome of mice with different genetic susceptibilities to the effects of fluoride

KHAN, Zohaib Nisar; LEITE, Aline de Lima; CHARONE, Senda; SABINO, Isabela Tomazini; MARTINI, Tatiana; PEREIRA, Heloísa Aparecida Barbosa da Silva; OLIVEIRA, Rodrigo Cardoso; BUZALAF, Marília Afonso Rabelo.

J. appl. oral sci; 24 (3), 2016

ABSTRACT A/J and 129P3/J mice strains have been widely studied over the last few years because they respond quite differently to fluoride (F) exposure. 129P3/J mice are remarkably resistant to the development of dental fluorosis, despite excreting less F in urine and having higher circulating F levels. T...

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