New metallophamaceutic reduced renal injury induced by non-steroidal anti-inflammatory
Acta cir. bras; 34 (12), 2019
Abstract Purpose To evaluate the effect of Rut-bpy (Cis-[Ru(bpy)2(SO3)(NO)]PF 6), a novel nitric oxide donor, able to modulate the histological changes caused by the NASID (meloxicam). Methods Wistar rats were assigned into three groups (n=6 rats/group): Sham group (saline solution), NSAID group (mel...
Antiinflamatorios no Esteroideos/efectos adversos, Fractales, Enfermedades Renales/inducido químicamente, Enfermedades Renales/patología, Enfermedades Renales/prevención & control, Meloxicam/efectos adversos, Donantes de Óxido Nítrico/farmacología, Compuestos Organometálicos/farmacología, Distribución Aleatoria, Ratas Wistar, Reproducibilidad de los Resultados, Rutenio/farmacología