BONEFILL ® block as alternative for bone substitute: a toxicological evaluation
Braz. J. Pharm. Sci. (Online); 54 (2), 2018
ABSTRACT Bone substitutes based on hydroxyapatite (HA) and Bonefill® (BO - inorganic bovine bone) associated with poly(lactic-co-glycolic acid) (PLGA) (HA/PLGA and BO/PLGA) were evaluated concerning cytotoxicity, genotoxicity and mutagenicity as potential candidates for bone repair. The materials were d...