Results: 6

Emodin inhibits bladder inflammation and fibrosis in mice with interstitial cystitis by regulating JMJD3

Acta cir. bras; 38 (), 2023
Purpose: Interstitial cystitis/bladder pain syndrome (IC/BPS) is a devastating urological chronic pelvic pain condition. In search of a potential treatment, we investigated the effect of emodin on IC/BPS inflammation and fibrosis, and explore the potential mechanism. Methods: An experimental model of int...

Endophytic bacteria promote growth and increase the aloin content of Aloe vera

Aloe vera is among the world’s economically most important medicinal plants, but as the growth of this plant and, consequently, the accumulation of metabolites is slow, we tested the hypothesis that root endophytic bacteria isolated from A. vera plants can promote growth and inc...

Emodin alleviates hypertrophic scar formation by suppressing macrophage polarization and inhibiting the Notch and TGF-β pathways in macrophages

Braz. j. med. biol. res; 54 (8), 2021
Hypertrophic scar (HS) formation is a common complication that develops after skin injury; however, there are few effective and specific therapeutic approaches for HS. Emodin has previously been reported to inhibit mechanical stress-induced HS inflammation. Here, we investigated the molecular mechanisms ...

Emodin protects H9c2 cells from hypoxia-induced injury by up-regulating miR-138 expression

Braz. j. med. biol. res; 52 (3), 2019
Myocardial infarction (MI) is a common presentation for ischemic heart disease, which is a leading cause of death. Emodin is a Chinese herbal anthraquinone used in several diseases. However, the effect of emodin in hypoxia-induced injury in cardiomyocytes has not been clearly elucidated. Our study aimed ...

Estudios in vitro de los mecanismos fotooxidantes y antioxidantes de los principios activos del aloe vera
Study in vitro of the mechanim phototoxicity and antioxidant of the pricipios actives of the aloe-emodina

Rev. Fac. Farm. (Merida); 45 (1), 2003
En este trabajo se determinó la fototoxicidad in vitro sobre eritrocitos humanos, de los principios activos del Aloe Vera, emodina aloe-emodina y rheina. Esto fue analizado por medio de espectrofotometría UV-Vis y fluorescencia en diferentes medios, bajo fuentes de irradiación Visible y UV-A. El estud...

Irritabilidad en el niño hasta los dos años de edad
Irritability in the small child

Homeopatía (B. Aires); 61 (1/2), 1996
El propósito de este trabajo es analizar el síntoma irritabilidad del lactante y del niño pequeño, y buscar las modalizaciones que nos ayuden a prescribir el remedio correspondiente. Se hace un breve resumen de los síntomas más característicos de los remedios más usados en este período de la vid...