A malária é um problema mundial de saúde, com 249 milhões de casos de infecção, ocasionando 608 mil mortes no ano de 2022. Causada pelo gênero Plasmodium, são cinco principais espécies causadoras da malária no ser humano, o Plasmodium malariae, Plasmodium ovale, Plasmodium knowlesi, Plasmodium ...
The receptor for advanced glycation end products (RAGE) is implicated in the pathogenesis of several chronic diseases including diabetes. The interaction between RAGE and advanced glycation end products (AGEs) promotes gene expression, enhances the release of proinflammatory molecules and causes the gene...
Diabetes Mellitus Experimental,
Receptor para Productos Finales de Glicación Avanzada/efectos de los fármacos,
Losartán/farmacología,
Enalapril/farmacología,
Ratas Sprague-Dawley,
Endotelio,
Aorta Abdominal,
Inmunohistoquímica,
Receptor para Productos Finales de Glicación Avanzada/metabolismo,
Inhibidores de la Enzima Convertidora de Angiotensina/farmacología,
Bloqueadores del Receptor Tipo 1 de Angiotensina II/farmacología,
d0120840
Fernández-Rodarte, Bernardo A;
Soto-Domínguez, Adolfo;
González-Navarro, Alejandro;
Mellado-Ayala, Maximiliano;
Piña-Mendoza, Edgar I;
Rodríguez-Rocha, Humberto;
Montes-de-Oca-Luna, Roberto;
Guerra-Leal, Jesús D;
Guzmán-López, Santos;
Elizondo-Omaña, Rodrigo E.
SUMMARY: Reactive Oxygen Species (ROS) are part of the functional balance of various systems, they can generate cellular damage by oxidative stress associated with disease processes such as atherosclerosis, cardiovascular disease, diabetes, and aging. Some studies report that copper induces damage to the...
To compare global endothelial function assessed by pulse wave analysis (PWA) using the ratio of endothelium dependent vasodilatation (EDV) to endothelium independent vasodilatation (EIV) in patients with hypercholesterolemia and controls. 92 subjects [46 hypercholesterolemics, 46 controls] were studied a...
Hemos leído con gran atención el artículo de los autores González Rey y otros, titulado: Disfunción endotelial en una etapa precoz del diagnóstico de hipertensión arterial. Resulta muy interesante el tratamiento de un tema básico de gran interés en la clínica a través del uso de biomarcadores ...
Abstract Background High dietary sodium intake can induce endothelial stiffness even without changes in blood pressure. Objectives To evaluate the effects of exercise training and chronic intake of sodium chloride solution on aortic morphology of male offspring of rat dams who consumed flaxseed during ...
Propolis from stingless bees (Heterotrigona itama) is a resinous compound that exhibits antihyperglycaemia, free radical scavenging, and cardioprotective properties. The effect of propolis on diabetic vessels has not been investigated. Thus, this research aimed to determine the effect of propolis supplem...
Endothelium is the inner layer of vessels that separates circulating blood from the rest of the
body tissues. Since its discovery, it has been involved in various functions, both systemic and
organ specific. Currently, endothelial damage and failure in its functions is considered a key
element in pathoph...
Graziani, D;
Ribeiro, J V V;
Cruz, V S;
Gomes, R M;
Araújo, E G;
Santos Júnior, A C M;
Tomaz, H C M;
Castro, C H;
Fontes, W;
Batista, K A;
Fernandes, K F;
Xavier, C H.
About 3000 tons of beans are not used in human food due to hardening. Several studies on bean-derived bioactive peptides have shown potential to treat some diseases, including those relying on oxidative dysfunctions. We assessed the effects of peptides extracted from hardened bean Phaseolus vulgaris (PV)...
