CD4+ T cells in aged or thymectomized recipients of allogeneic stem cell transplantations
Biol. Res; 48 (), 2015
BACKGROUND: CD4+CD25highFOXP3+ regulatory T (Treg) cells, which include thymus-derived and peripherally induced cells, play a central role in immune regulation, and are therefore crucial to prevent graft-versus-host disease (GVHD). The increasing use of allogeneic hematopoietic stem cell transplantation ...