Vedolizumabe e anticorpos anti-TNF-α (infliximabe, adalimumabe, certolizumabe pegol). Indicação: Tratamento pessoas com doença de Crohn com falha a um agente biológico anti-TNF-α em tratamento prévio. Pergunta: Para adultos com doença de Crohn moderada a grave com falha terapêutica para anticorp...
ABSTRACT Background and Aims The present systematic review and meta-analysis was designed to estimate the safety and effectiveness of ustekinumab in the treatment of Crohn disease (CD) in clinical trials and observational studies. Methods We retrieved all the related publications from the PubMed, Cochr...
Los antagonistas del Factor de Necrosis Tumoral-α, son medicamentos que en los últimos años han tenido un incremento de su uso en pacientes con condiciones inflamatorias inmunomediadas en pediatría, como la Artritis Idiopática Juvenil y la Enfermedad Inflamatoria...
A doença de Crohn é uma patologia caracterizada pela inflamação transmural do trato gastrointestinal, compondo o espectro
das doenças inflamatórias intestinais. Nos casos mais graves,
dispõe de tratamento com uso de agentes biológicos e imunomoduladores que podem à reativação ou exacerbaçã...
ABSTRACT BACKGROUND: A healthy diet is recommended for patients with Crohn's disease (CD) in remission. OBJECTIVE: To evaluate the diet quality of patients with CD. METHODS: Cross-sectional study with patients with CD and clinical remission using the biological agent infliximab. The diet quality wa...
Abstract As the treatment of infectious and parasitic diseases improved, the prevalence of these conditions declined. However, with the expansion of the use of immunobiologicals, opportunistic infections have emerged, especially under atypical presentations. The present study reports the case of a patien...
ABSTRACT BACKGROUND: The rates of postoperative endoscopic recurrence (PER) in patients with Crohn's disease (CD) are consistent. Anti-TNF therapy has been increasingly used in the postoperative setting, despite the lack of robust data in the literature on the measurement of trough levels and consequen...
Introducción: La enfermedad de Crohn presenta una incidencia en aumento en los últimos años en los países industrializados. La afectación ileocecal es la forma de presentación más frecuente en esta patología. En una primera instancia los pacientes pueden recibir tratamiento médico, pero un porce...
Lucca, Fernando de Azevedo;
Malaguti, Carla;
Chebli, Liliana Andrade;
Reboredo, Maycon Moura;
Pinheiro, Bruno Valle;
Ribeiro, Tarsila Campanha da Rocha;
Azevedo, Felipe Meirelles de;
Corrêa, José Otávio do Amaral;
Gaburri, Pedro Duarte;
Chebli, Julio Maria Fonseca.
SUMMARY AIM: To compare the level of physical activity (PA), exercise capacity, and body composition before and after infliximab-induced clinical remission in patients with Crohn's disease (CD). METHODS: This prospective longitudinal study evaluated 44 adult outpatients with active CD before infliximab...