Results: 3

Coumarin analogue 3-methyl-7H-furo[3,2-g]chromen-7-one as a possible antiparkinsonian agent

Biomédica (Bogotá); 39 (3), 2019
Abstract Introduction: Parkinson's disease is the second most common neurodegenerative disease. Monoamine oxidase B inhibitors are used in the treatment of this disease concomitantly with levodopa or as monotherapy. Several substituted coumarins have shown activity as inhibitors of monoamine oxidase B. ...

Effect of adenosine A2A receptor antagonists on motor disorders induced by 6-hydroxydopamine in rat

Acta cir. bras; 31 (2), 2016
PURPOSE: To investigate the role of adenosine A2A receptors on 6-OHDA-induced motor disorder in rat. METHODS: In order to induce experimental model of Parkinson's disease, 6-hydoxydopamine (8 μg/rat) was injected unilaterally into the SNc. After three weeks as a recovery period, 6-OHDA-induced brady...

Importancia de la infección por la bacteria chlamydophila pneumoniae en las enfermedades cardíacas de origen aterosclerótico

Considerar la aterosclerosis como una enfermedad inflamatoria, ha renovado el interes en el rol que agentes infecciosos como la Chlamydophila pneumoniae (C pneumoniae) pueden jugar en el desarrollo del ateroma. El objeto de esta tesis fue investigar la asociación entre la C pneumoniae y la enfermedad ca...