Results: 10

Pretreatment with kuanxiong aerosol protects against coronary microvascular dysfunction

This study investigates the efficacy and mechanisms of Kuanxiong Aerosol (KXA) on coronary microvascular dysfunction (CMD) in rats. Thirty-two Sprague-Dawley rats were divided into control, model, KXA, and nicorandil groups, receiving respective treatments for three weeks. The CMD...

El tratamiento basado en metas de colesterol LDL no sería inferior a las dosis altas de estatinas en pacientes con enfermedad coronaria
Treat-to-target LDL-C would not be inferior to high-intensity statin in patients with coronary artery disease

Prevalence of pharmacological adherence in patients with coronary artery disease and associated factors

Objective: to assess the prevalence of pharmacological adherence in patients with coronary artery disease and to identify factors associated with adherence. Method: a crosssectional, correlational study, including 198 patients with a previous diagnosis of coronary artery disease. Pharmacological adheren...

Medication regimen complexity of coronary artery disease patients

ABSTRACT Objective: To determine the factors associated with the high complexity of medication regimen in patients with coronary artery disease. Methods: A cross-sectional study was carried out in a multiprofessional cardiology outpatient clinic, in the Secondary Care of the Unified Health System, wher...

Comunicación breve: aspirina en la prevención primaria de la enfermedad ateroesclerótica cardiovascular y su automedicación: Un problema por solucionar
Brief communication: aspirin in primary prevention of cardiovascular atherosclerotic disease and its self-medication A problem to solve

Gac. méd. Caracas; 127 (3), 2019
Millones de personas, sin indicación médica, toman aspirina para la prevención primaria de la enfermedad ateroesclerótica cardiovascular. La Sociedad Europea de Cardiología no la recomienda para prevención primaria de esta entidad y las Guías del ACC/ AHA sobre Prevención Primaria de la Enfermeda...

Ranolazina como terapia antianginosa adicional en pacientes con enfermedad coronaria estable sintomática

Medwave; 18 (7), 2018
INTRODUCCIÓN: La enfermedad coronaria estable posee varios tratamientos con beneficio probado tanto en mortalidad como en incidencia de eventos agudos. Sin embargo, el control de los síntomas, especialmente en aquellos que no responden a terapia de primera línea, sigue siendo controvertido. Este resum...

Perfil contemporâneo da intervenção coronária percutânea em octogenários

Introdução: Com o aumento da longevidade observado nas últimas décadas, as intervenções coronárias percutâneas (ICP) em octogenários são cada vez mais indicadas. Objetivo: Traçar o perfil clínico-epidemiológico-angiográfico e os principais detalhes associados à ICP dos pacientes octogen...

Decreased platelet responsiveness to clopidogrel correlates with CYP2C19 and PON1 polymorphisms in atherosclerotic patients

Braz. j. med. biol. res; 50 (1), 2017
Clopidogrel and aspirin are the most commonly used medications worldwide for dual antiplatelet therapy after percutaneous coronary intervention. However, clopidogrel hyporesponsiveness related to gene polymorphisms is a concern. Populations with higher degrees of genetic admixture may have increased prev...

Myocardial bridging

Abstract Myocardial bridging is rare. Myocardial bridges are most commonly localized in the middle segment of the left anterior descending coronary artery. The anatomic features of the bridges vary significantly. Alterations of the endothelial morphology and the vasoactive agents impact on the progressio...

Stent farmacológico para o tratamento da doença arterial coronariana (DAC)

CONTEXTO: A Doença Arterial Coronariana (DAC) é em 90% dos casos, resultante da oclusão ou do estreitamento das artérias coronarianas. Os objetivos do tratamento da DAC são prevenir o Infarto agudo do miocárdio (IAM), reduzir a mortalidade, os sintomas e a ocorrência da isquemia miocárdica. Esses...