The expression of endothelial and inducible nitric oxide synthase and apoptosis in intestinal ischemia and reperfusion injury under the action of ischemic preconditioning and pentoxifylline
Acta cir. bras; 32 (11), 2017
Abstract Purpose: To investigate the expression of nitric oxide synthase (NOS) and apoptosis associated with ischemic preconditioning (IPC) and pentoxifylline (PTX) in intestinal ischemia (I) and reperfusion (R) injury. Methods: Thirty male rats were assigned to 5 groups: (CG), no clamping of the sup...
Apoptosis/efectos de los fármacos, Enfermedades Intestinales/prevención & control, Intestinos/irrigación sanguínea, Precondicionamiento Isquémico, Óxido Nítrico Sintasa/metabolismo, Pentoxifilina/uso terapéutico, Apoptosis/fisiología, Modelos Animales de Enfermedad, Inmunohistoquímica, Enfermedades Intestinales/enzimología, Intestinos/patología, ARN Mensajero/análisis, Ratas Wistar, Vasodilatadores/uso terapéutico