BACKGROUND: The frequency of glomerular diseases is dynamic and varies according to geographic area. AIM: To evaluate the frequency of primary and secondary glomerulopathies, their demographic profile and main clinical characteristics. MATERIAL AND METHODS: Renal biopsies from native kidneys performed be...
Se comunica una serie de tres casos clínicos que consultaron al servicio de Reumatología por compromiso orbitario y renal. Uno de ellos presentó pseudotumor orbitario con proteinuria en rango nefrótico; se realizó biopsia y se encontró infiltrado linfoplasmocitario denso y fibrosis estoriforme con ...
Amiloidosis/diagnóstico,
Sarcoidosis/diagnóstico,
Enfermedad Relacionada con Inmunoglobulina G4/diagnóstico,
Enfermedades Orbitales/diagnóstico,
Enfermedades de la Piel/diagnóstico,
Enfermedades Renales/diagnóstico,
Enfermedad Relacionada con Inmunoglobulina G4/patología,
Enfermedad Relacionada con Inmunoglobulina G4/tratamiento farmacológico,
Enfermedades de la Piel/patología,
Enfermedades de la Piel/tratamiento farmacológico,
Artritis Reumatoide/diagnóstico,
Artritis Reumatoide/tratamiento farmacológico,
Enfermedades Renales/tratamiento farmacológico,
Diagnóstico Diferencial,
Enfermedades Renales/patología,
Amiloidosis/tratamiento farmacológico,
Amiloidosis/patología
Renal fibrosis is one of the most significant pathological changes after ureteral obstruction. Transforming growth factor-β (TGF-β) signaling pathway plays essential roles in kidney fibrosis regulation. The aims of the present study were to investigate effects of microRNA-302b (miR-302b) on ren...
Línea Celular,
Transición Epitelial-Mesenquimal,
Fibrosis,
Riñón/patología,
Enfermedades Renales/genética,
Enfermedades Renales/patología,
MicroARNs/genética,
Transducción de Señal,
Proteínas Smad,
Factor de Crecimiento Transformador beta/metabolismo,
Obstrucción Ureteral/patología
Chronic kidney disease (CKD) is characterized by irreversible morphostructural lesions that can progressively evolve to chronic renal insufficiency and kidney failure. It is known that the heart and kidneys are closely related, and that communication between these organs occurs through a variety of pathw...
ABSTRACT Sarcoidosis is a multisystem granulomatous disease characterized by epithelioid noncaseating granulomas associated with clinical and radiologic findings. The cause of this disease is still uncertain. Sarcoidosis affects mostly lungs and lymph nodes and is not usually considered a urological dise...
Biopsia,
Enfermedad Crónica,
Hipercalcemia/diagnóstico,
Hipercalcemia/patología,
Hipercalciuria/diagnóstico,
Hipercalciuria/patología,
Enfermedades Renales/diagnóstico,
Enfermedades Renales/patología,
Enfermedades Renales/terapia,
Sarcoidosis/diagnóstico,
Sarcoidosis/patología,
Sarcoidosis/terapia
Amyloidosis comprises a group of disorders that accumulate modified autologous proteins in organs, mainly the kidneys. Few studies have addressed the amyloid compartmental distribution and associated clinical outcomes. The aim of this study was to present a case series of renal amyloidosis correlating hi...
Abstract Gallic acid (GA), as a strong antioxidant, was selected in this study to investigate its possible nephroprotective effects against gentamicin (GM)-induced nephrotoxicity. Twenty-four rats were separated into three groups (n=8): group 1 (control group) received saline (0.5 mL/day), group 2 (GM gr...
Ácido Gálico/química,
Gentamicinas/efectos adversos,
Ácido Gálico/uso terapéutico,
Antioxidantes/uso terapéutico,
Estrés Oxidativo/efectos de los fármacos,
Enfermedades Renales/inducido químicamente,
Enfermedades Renales/tratamiento farmacológico,
Enfermedades Renales/patología,
Ratas Wistar,
Biomarcadores,
Modelos Animales de Enfermedad,
Lipoproteínas HDL,
Colesterol,
Lipoproteínas LDL,
Antibacterianos/efectos adversos
Abstract Lipoprotein glomerulopathy (LPG) is an uncommon cause of nephrotic syndrome and/or kidney failure. At microscopy, LPG is characterized by the presence of lipoprotein thrombi in dilated glomerular capillaries due to different ApoE mutations. ApoE gene is located on chromosome 19q13.2, and can be ...
Apolipoproteínas E/genética,
Hipolipemiantes/uso terapéutico,
Enfermedades Renales/complicaciones,
Enfermedades Renales/genética,
Enfermedades Renales/patología,
Enfermedades Renales/terapia,
Fallo Renal Crónico/etiología,
Fallo Renal Crónico/cirugía,
Trasplante de Riñón,
Mutación,
Factores Sexuales,
Resultado del Tratamiento
Obesity is a modifiable risk factor for the development and progression of kidney disease. Obesity may harm kidneys in individuals without hypertension, diabetes, or pre-existing renal disease. Ginger, Zingiber officinale, has many beneficial pharmaceutical benefits. This study aimed to evaluate the Zing...
Obesidad/complicaciones,
Dieta Alta en Grasa/efectos adversos,
Zingiber officinale/química,
Extractos Vegetales/farmacología,
Ratas Sprague-Dawley,
Enfermedades Renales/tratamiento farmacológico,
Enfermedades Renales/patología,
Microscopía Electrónica de Transmisión,
Riñón/patología,
Peso Corporal,
Leptina/análisis,
Factor de Necrosis Tumoral alfa/análisis,
Creatinina/análisis
Goodpasture Syndrome is described as a single episode disease entity. It is diagnosed with the demonstration of antiglomerular basement (anti-GBM) antibodies in plasma or renal tissue. Although the recurrence of anti-GBM disease is rare, it has been reported in up to 3% of cases. Recurrence with negative...
Enfermedad por Anticuerpos Antimembrana Basal Glomerular/patología,
Autoanticuerpos/análisis,
Antibacterianos/uso terapéutico,
Enfermedad por Anticuerpos Antimembrana Basal Glomerular/diagnóstico por imagen,
Enfermedad por Anticuerpos Antimembrana Basal Glomerular/tratamiento farmacológico,
Biopsia,
Ciclofosfamida/uso terapéutico,
Técnica del Anticuerpo Fluorescente,
Enfermedades Renales/patología,
Glomérulos Renales/patología,
Prednisona/uso terapéutico,
Recurrencia,
Combinación Trimetoprim y Sulfametoxazol/uso terapéutico
