LILACS – Literatura Latinoamericana y del Caribe de Ciencias de la Salud

Protective effects of tigernut (Cyperus esculentus) on Bisphenol A- induced testicular toxicity in Wistar rats

Abraham, Abigaíl; Idaguko, Chika Anna.

Int. j. med. surg. sci. (Print); 11 (2), 2024

Bisphenol A (BPA) have been reported to induced reprotoxicity in rats. This study was conducted to find out the ameliorative properties of aqueous extract of Cyperus esculentus (tigernut) on BPA induced testicular toxicity in Wistar rats.Methods: Twenty male rats were divided randomly into 4 groups (n=5)...

Enfermedades Testiculares/prevención & control, Testículo/efectos de los fármacos, Cyperus/química, Extractos Vegetales/farmacología, Extractos Vegetales/aislamiento & purificación, Enfermedades Testiculares/inducido químicamente, Enfermedades Testiculares/metabolismo, Enfermedades Testiculares/patología, Testículo/metabolismo, Antiinflamatorios/aislamiento & purificación, Antiinflamatorios/farmacología, Antioxidantes/aislamiento & purificación, Antioxidantes/farmacología, Modelos Animales de Enfermedad, Bisfenol A Glicidil Metacrilato/efectos adversos, Ratas Wistar, Espermatozoides/efectos de los fármacos, Espermatozoides/metabolismo, Espermatozoides/patología

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Chloroquine ameliorates adriamycin-induced testicular damage by suppressing the inflammation and apoptosis in rats: a histological, immunohistochemical and biochemical study

SUMMARY: Adriamycin (ADR) is an anthracycline antibiotic used for treatment of many types of cancer. However, its applications may damage to healthy tissues. Chloroquine (CLQ) is an anti-inflammatory agent used in treatment of many inflammation associated diseases such as malaria and rheumatoid arthritis...