Chloroquine ameliorates adriamycin-induced testicular damage by suppressing the inflammation and apoptosis in rats: a histological, immunohistochemical and biochemical study
Int. j. morphol; 39 (4), 2021
SUMMARY: Adriamycin (ADR) is an anthracycline antibiotic used for treatment of many types of cancer. However, its applications may damage to healthy tissues. Chloroquine (CLQ) is an anti-inflammatory agent used in treatment of many inflammation associated diseases such as malaria and rheumatoid arthritis...
Enfermedades Testiculares/inducido químicamente, Enfermedades Testiculares/tratamiento farmacológico, Cloroquina/administración & dosificación, Doxorrubicina/efectos adversos, Inflamación, Apoptosis/efectos de los fármacos, Antibióticos Antineoplásicos/efectos adversos, Etiquetado Corte-Fin in Situ, Interleucina-6, Factor de Necrosis Tumoral alfa, Inmunohistoquímica, Ensayo de Inmunoadsorción Enzimática, Ratas Wistar